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未破裂卵泡黄素化综合征中医证型与证素分布特点的文献研究
Distribution Characteristic of Traditional Chinese Medicine Syndromes and Syndrome Elements of Luteinized Unruptured Follicle Syndrome: A Literature Research
投稿时间:2021-02-17  修订日期:2021-05-12
DOI:
中文关键词:  未破裂卵泡黄素化综合征  中医证型  中医证素  文献研究
英文关键词:Luteinized unruptured follicle syndrome  LUFS  TCM syndrome  TCM syndrome element  literature research
基金项目:浙江省中医药科技计划项目(No.2020Z8186)
作者单位邮编
徐哲昀 浙江中医药大学 310053
张盈盈 浙江中医药大学 
王颖巨 浙江中医药大学 
雷蕾 浙江中医药大学 
俞佳 浙江省中西医结合医院 
丁彩飞 浙江省中西医结合医院 310003
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中文摘要:
      目的:基于文献探究未破裂卵泡黄素化综合征(LUFS)的证型、证素分布特点。方法:检索万方数据知识服务平台、中国知网、维普中文期刊服务平台,选择自建库至2020年12月包含LUFS中医证型的文献,提取证型、证素后进行频数分析、聚类分析。结果:共纳入83篇文献,涉及中医证型26个,常见中医证型为肾虚血瘀证、肝郁证、肾虚肝郁证、血瘀证、肾虚证、痰湿证。提取病位证素5个,常见的是胞宫、肾、肝;提取病性证素11个,常见的是精亏、血瘀、气滞、阳虚、湿、阴虚。常见证素组合是四证素组合,其中肾+胞宫+精亏+血瘀出现频率最高。通过聚类分析将高频证素聚为3类:(1)肝、气滞;(2)脾、阳虚、阴虚、痰、湿;(3)肾、胞宫、精亏、血瘀。结论:LUFS的中医证候特点为虚实夹杂,虚证主要为肾、肝、脾之精气阴阳亏虚,实证主要为胞宫气滞血瘀、痰湿壅阻,辨证要点可概括为“虚、瘀、郁、湿”。
英文摘要:
      Objective: To explore the distribution characteristic of Traditional Chinese Medicine (TCM) syndromes and syndrome elements of luteinized unruptured follicle syndrome (LUFS) based on literatures. Methods: Literatures containing TCM syndromes and syndrome elements of LUFS were retrieved from Wangfang Data, CNKI and VIP from the beginning of establishment of library to December 2020. Then the names of TCM syndromes and syndrome elements were extracted and frequency statistics, cluster analysis were conducted. Results: Totally 83 articles were included, involving 26 syndrome names. The common syndromes were kidney deficiency-blood stasis syndrome, liver-qi stagnation syndrome, kidney deficiency-liver stagnation syndrome, blood stasis syndrome, kidney deficiency syndrome and phlegm-dampness syndrome. There were 5 location syndrome elements and 11 nature syndrome elements. The common location syndrome elements were uterus, kidney, liver and the common nature syndrome elements were essence deficiency, blood stasis, qi stagnation, yang deficiency, dampness, yin deficiency. The common syndrome element combination was four syndrome element combination, among which the combination of kidney, uterus, essence deficiency and blood stasis occurred most frequently. There were 6 types of syndrome elements by cluster analysis: (1) liver, qi stagnation; (2) phlegm, dampness; (3) spleen, yang deficiency; (4) yin deficiency; (5) uterus, blood stasis; (6) kidney, essence deficiency. Conclusion: The characteristic of TCM syndromes and syndrome elements of LUFS is combination of deficiency and excess. Deficiency syndromes are mainly deficiency of essence, yin and yang in kidney while excess syndromes are mainly blood stasis, qi stagnation, phlegm-dampness. The key points of syndrome differentiation can be summarized as deficiency, blood stasis, deficiency and phlegm-dampness.
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