| 王芮,金文杰,冯君,应锡标.紫衫烷类药物相关周围神经损伤的康复研究进展[J].浙江中西医结合杂志,2023,33(12): |
| 紫衫烷类药物相关周围神经损伤的康复研究进展 |
|
| 投稿时间：2023-04-27 修订日期：2023-07-21 |
| DOI： |
| 中文关键词: 紫杉烷类药物 周围神经病变 康复评定 康复治疗 |
| 英文关键词:Taxanes peripheral neuropathy rehabilitation evaluation rehabilitation therapy |
| 基金项目: |
|
| 摘要点击次数: 166 |
| 全文下载次数: 0 |
| 中文摘要: |
| 紫杉烷类作为一种抗肿瘤化学治疗的基石药物，被较广泛应用于乳腺癌等多种恶性肿瘤的治疗中，能显著提高患者的生存率。然而，随着紫衫烷类药物的应用，其不良反应也逐渐显现。其中紫杉烷类药物所致的周围神经损伤（taxane-induced peripheral neuropathy,TIPN）可导致患者出现多种功能障碍，严重影响了患者的生存质量，目前尚无明确的TIPN的规范康复诊疗方案。现将目前紫杉烷类药物所致的周围神经损伤机制、功能障碍、康复评定及康复治疗进展进行综述，以期找到更有效的康复治疗手段，制定规范的康复诊疗策略，提高患者的生存质量。 |
| 英文摘要: |
| Taxanes, as a cornerstone of anti-tumor chemotherapy, are widely used in the treatment of breast cancer and other malignant tumors, which can significantly improve the survival rate of patients. However,with the application of taxanes, the adverse reactions also gradually appear. Taxane-induced peripheral neuropathy (TIPN) can cause a variety of functional disorders in patients, which seriously affects the quality of life of patients.At present, there is no clear standardized rehabilitation therapy for TIPN. This article reviews the current peripheral nerve injury mechanisms,dysfunction,rehabilitation assessment and rehabilitation therapy progress caused by taxanes, in order to find more effective rehabilitation treatment means, formulate standard rehabilitation diagnosis and therapy strategies, and improve the quality of life of patients. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
