| 谢佳婷,谢小红.基于文献研究分析中药外敷治疗急性乳腺炎的用药规律[J].浙江中西医结合杂志,2022,32(1): |
| 基于文献研究分析中药外敷治疗急性乳腺炎的用药规律 |
| Analysis of a Chinese medicine external application for acute mastitis based on a literature study |
| 投稿时间：2021-05-30 修订日期：2021-07-29 |
| DOI： |
| 中文关键词: 急性乳腺炎 中药外敷 用药规律 聚类分析 关联分析 |
| 英文关键词:Acute mastitis Chinese medicine external application Medication pattern Cluster analysis Association analysis. |
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| 中文摘要: |
| 目的 探索分析中药外敷治疗急性乳腺炎的用药规律和特点。方法 检索中国知识资源总库(CNKI)、万方数据知识服务平台、维普网中文科技期刊关于中药外敷治疗急性乳腺炎的临床研究文献,利用Microsoft Excel2016软件建立数据库,对用药频次及类别、中药性味归经、联合治疗情况进行统计分析。应用IBM SPSS Statistics 25.0软件对高频药物进行系统聚类分析,IBM SPSS Modeler18.0软件进行关联规则分析。结果 共纳入文献105篇,涉及用药125味,使用频次共646次。使用频次排名前3位的中药为大黄、黄柏、蒲公英。药物性味以苦寒为主,主要归肝、胃、肺经。联合治疗以手法通乳为主。聚类分析将18味高频药物分为4大类。关联分析得到高频药对共有6对。结论 中药外敷治疗急性乳腺炎以清热解毒、活血化瘀为主,药物多苦寒,归肝、胃、肺经,重在针对实证病机及主要症状,同时重视补虚、化痰、理气等药物的配伍使用。 |
| 英文摘要: |
| Objective To analyze the medication pattern and characteristics of traditional Chinese medicine external dressing for the treatment of acute mastitis. Methods The clinical research literature on the application of traditional Chinese medicine external dressing for the treatment of acute mastitis was retrieved from CNKI, WanFang DATA, VIP. The databases were established with Microsoft excel 2016, and statistical analysis was performed on frequency and category of drugs, Four Properties, Five Tastes and Channel Distribution in Chinese Herbal, and combined treatment. IBM SPSS statistics 25.0 was used for hierarchical clustering analysis of high-frequency drugs, and IBM SPSS modeler 18.0 was used for association rules analysis. Results A total of 105 literatures were included, involving 125 kinds of traditional Chinese medicine which was used 646 times. The top three most frequently used herbs were Rheum officinale,Phellodendron,Dandelion. Herbs were predominantly bitter, cold in properties. The channel-tropism of medicine was mostly liver, stomach, lung. Combination therapy was based on manual breast opening. Cluster analysis classified the 18 high-frequency drugs into 4 major classes. Association analysis yielded a total of 6 high frequency drug pairs. Conclusion Chinese medicine external application for acute mastitis is based on clearing away the heat-evil, quickening the blood and transforming stasis. Herbs were predominantly bitter, cold in properties. The channel-tropism of medicine was mostly liver, stomach, lung. Aiming at the pathogenesis and main symptoms of the syndrome, at the same time, emphasis is placed on the compatibility of the use of medicines such as tonifying deficiency, resolving phlegm and regulating qi. |
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