黄挺,程向东,杨翀.槐耳抗肿瘤活性部位的筛选研究[J].浙江中西医结合杂志,2021,31(7): |
槐耳抗肿瘤活性部位的筛选研究 |
Study on screening of anti-tumor parts from Huaier. |
投稿时间:2021-01-12 修订日期:2021-06-08 |
DOI: |
中文关键词: 槐耳 抗肿瘤活性 增殖抑制 |
英文关键词:Huaier antitumor activity proliferation inhibition |
基金项目:国家自然科学基金项目(面上项目,重点项目,重大项目) |
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中文摘要: |
目的 研究槐耳不同提取分离部位对不同肿瘤细胞的体外增殖抑制作用, 筛选槐耳抗肿瘤有效部位。方法 方法采用溶剂法对槐耳进行不同部位分离,利用CCK-8法检测槐耳不同提取物对肿瘤细胞的抑制作用。结果 槐耳不同提取物对肿瘤细胞均有不同程度的抑制作用,其中,醇水双提部位抗肿瘤活性最高。结论 槐耳中抗肿瘤的有效部位是醇水双提部位,且其对不同肿瘤细胞的体外增殖抑制作用呈一定的浓度依赖作用。 |
英文摘要: |
OBJECTIVE Study on the inhibitory effect of different parts of Huaier extracts on the proliferation of tumor cells. To screen the anti-tumor active parts from Huaier by anti-tumor experimental model in vitro. METHODS CCK-8 assay was used to assay the growth of cancer cells. RESULT Huaier extracts on tumor cells have different degrees of inhibition, The ethanol and water extracts showed the highest antitumor activity. CONCLUSION The effective parts of anti tumor is Huaier alcohol and water extract, and its inhibitory effect on different tumor cells in vitro proliferation in a concentration dependent effect. |
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