| 陈文,严静东,崔凤.松果体区肿瘤的影像学特征与临床及病理的相关性分析[J].浙江中西医结合杂志,2021,31(4): |
| 松果体区肿瘤的影像学特征与临床及病理的相关性分析 |
| The correlation analysis of imaging,clinical and pathologic features in pineal region tumor |
| 投稿时间：2020-10-12 修订日期：2020-12-15 |
| DOI： |
| 中文关键词: 松果体 脑肿瘤 病理学 体层摄影术 X线计算机 磁共振成像。 |
| 英文关键词:Pineal body Brain tumor Pathology Tomography X-ray computed Magnetic resonance imaging. |
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| 中文摘要: |
| 目的 探讨松果体区肿瘤的影像学特征与临床和病理的相关性，提高松果体区肿瘤的术前影像学诊断效能。 方法 回顾性分析113例经手术病理证实的松果体区肿瘤的影像、临床及病理资料，包括生殖细胞肿瘤44例，松果体实质细胞肿瘤32例，神经胶质肿瘤26例，脑膜肿瘤11例；所有病例均行MR平扫及增强扫描，其中74例患者行头颅CT平扫。 结果 113例松果体区肿瘤，男性77例，女性36例，平均年龄24.2岁。共有46例肿瘤出现钙化，生殖细胞肿瘤（28/44）、松果体实质细胞肿瘤（9/32）、神经胶质肿瘤（6/26）及脑膜肿瘤（3/11），生殖细胞肿瘤和松果体实质细胞肿瘤在钙化位置及形态上的差异有统计学意义（P<0.05）。5例生殖细胞瘤出现“蝶形征”改变（5/21）。32例生殖细胞肿瘤出现囊变坏死（32/44），其中有16例非生殖细胞瘤性生殖细胞肿瘤出现多发小囊状改变（16/26）。5例混合性生殖细胞肿瘤出现了“蜂窝状强化”（5/16）。 结论 松果体区肿瘤病理类型多样，影像学表现有一定特征性，影像与临床病理结合，有助于提高松果体区肿瘤的术前诊断。 |
| 英文摘要: |
| Objective To explore the clinical and imaging features of pineal region tumors and improve the accuracy of preoperative imaging diagnosis of pineal region tumors. Meththods The clinical, imaging and pathological data of 113 cases of pineal region tumor confirmed by operation and pathology were retrospectively analyzed, and relevant literatures were reviewed. Including germ cell tumor (44 cases), pineal parenchymal cell tumor (32 cases), glial tumor (26 cases) and meningeal tumor (11 cases). All patients underwent MR plain scan and enhanced scan, and 74 patients underwent CT plain scan. Results In those 113 cases，77 were men，36 were women，the average age was 24.2. 46 tumors showed calcification, including germ cell tumor (28/44), pineal parenchymal tumor (9/32), glial tumor (6/26) and meningeal tumor (3/11). The differences in calcification location and morphology between germ cell tumor and pineal parenchymal tumor were statistically significant (P<0.05).5 germ cell tumor showed "butterfly sign"（5/21）.Cystic necrosis was observed in 32 germ cell tumors (32/44), and multiple small cystic changes were observed in 16 non-germ cell tumors (16/26).Five cases of mixed germ cell tumors showed "honeycomb enhancement" (5/16). Conclusion The pathological types of tumors in the pineal region are diverse, but often with certain characteristics. It is helpful to improve the preoperative diagnosis of pineal region tumor by combining the clinical data such as gender and age. |
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