| 陈会芳,朱永琴.基于数据挖掘探讨盛丽先教授治疗小儿过敏性紫癜用药规律[J].浙江中西医结合杂志,2021,31(4): |
| 基于数据挖掘探讨盛丽先教授治疗小儿过敏性紫癜用药规律 |
| Based on data mining, study on the rule of Shenglixian professor in the treatment of allergic purpura in children |
| 投稿时间：2020-08-05 修订日期：2021-03-09 |
| DOI： |
| 中文关键词: 小儿过敏性紫殿 盛丽先 名中医经验 关联规则 聚类分析 |
| 英文关键词:Children allergic purple temple ShengLi xian Famous Traditional Chinese medicine experience Association rules Clustering analysis. |
| 基金项目:浙江中医药科技计划科研基金项目 |
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| 中文摘要: |
| 目的 探讨挖掘师盛丽先教授治疗小儿过敏性紫殿的处方用药规律，传承名医经验，为中医临床治疗小儿过敏性紫殿提供思路；方法 收集2015年1月1日-2019年12月31日期间盛丽先教授门诊的过敏性紫癜患儿临床信息，共计248例，1020诊次，并将患儿就诊信息转化成有效数据表，对药物累计频数、药物性味、归经及其功效归类进行描述性分析，对前29味高频数药物采用系统聚类、关联规则分析，并对全部药物进行复杂网络分析得出核心处方。结果 共筛选出248例过敏性紫癜患儿，1020诊次共用中药167种，累积用药12724次，其中最多者为甘草，其后依次为玉米须、白茅根等。药性使用频数最多者为“寒”，药味使用频数最多者为“甘”，归经使用频数最多者为“肺”与“脾”，功效分类频数最多者为“补虚药”“清热药”。聚类分析将前29味高频药物分为6类，涉及四逆散、玉屏风散、二陈汤、六味地黄汤、小柴胡汤；关联规则分析结果涉及方剂桔梗甘草汤、玉屏风散等；复杂网络分析结果所得核心方药。结论 盛丽先教授治疗小儿以过敏性紫殿以清热凉血为主，盛丽先教授治疗小儿过敏性紫殿喜用药物味甘、苦，性寒、平，药物归经为肺、脾经，常用药物为清热药。 |
| 英文摘要: |
| Objective To explore the prescription law of excavator Professor Sheng Lixian in the treatment of allergic Purple temple in children, inherit the experience of famous doctors, and provide ideas for TCM clinical treatment of allergic Purple Temple in children. Methods collect on January 1, 2015 - December 31, 2019 ShengLi professor first outpatient service during the period of children with allergic purpura clinical information, a total of 248 cases, 1020 clinical time, and the children clinic information into effective data table, the drugs, accumulated frequency, sexual flavour, through descriptive analysis and its efficacy are classified, the former 29 taste high frequency drug use system clustering analysis and association rules, and complex network analysis it is concluded that the core of all drugs prescription. Results A total of 248 children with allergic purpura were selected, 167 kinds of Traditional Chinese medicine were used for 1020 diagnoses, and 12,724 times were accumulated. The most patients were licorice root, followed by corn stalk and white root. The most frequently used medicine is "cold", the most frequently used medicine is "gan", the most frequently used medicine is "lung" and "spleen", and the most frequently used medicine is "deficiency medicine" and "heat clearing medicine". Cluster analysis divided the first 29 high-frequency drugs into 6 categories, involving Sini powder, Jade Screen powder, Erchen soup, Liuwei dihuang soup, xiaochaihu soup. The analysis results of association rules involved prescriptions such as Radix Platycodonis liquorice soup and Jade Screen powder. Complex network analysis results of the core formulas. Conclusion In the treatment of children with allergic zidian, Professor Shengli gave priority to clearing away heat and cooling blood. In the treatment of children with allergic Zidian, Professor Shengli used drugs for sweet and bitter taste, cold and flat properties. The drugs belong to the lung and spleen meridiums, and the commonly used drugs are heat-clearing drugs. |
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