| 陈馨.尿感宁颗粒辅助输尿管软镜钬激光碎石术治疗肾结石合并尿路感染的疗效分析[J].浙江中西医结合杂志,2021,31(1): |
| 尿感宁颗粒辅助输尿管软镜钬激光碎石术治疗肾结石合并尿路感染的疗效分析 |
| Effect analysis of flexible ureteroscopy and holmium laser lithotripsy assisted by Urine ganning granule in the treatment of renal calculi complicated with urinary tract infectionCHEN Xin, LI Ming, Wang Xiao, ZHAI Menghe, GUO Xiao, Jiang Wenhua, Department of Urology,the Second Affiliated Hospital of Jiaxing Medical College,Jiaxing,314000,China |
| 投稿时间：2020-08-05 修订日期：2020-12-08 |
| DOI： |
| 中文关键词: 肾结石 输尿管镜 碎石术，激光 尿感宁颗粒 |
| 英文关键词:Renal calculi Ureteroscopy Lithotripsy Holmium laser Urine ganning granule |
| 基金项目:浙江省医学会临床科研资金项目(No. 2018ZYC-A91) |
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| 中文摘要: |
| 目的 探讨输尿管软镜钬激光碎石联合尿感宁颗粒治疗肾结石伴尿路感染的疗效和安全性。方法 回顾性分析2018年12月至2019年04月我院收治的80例合并尿路感染的肾结石应用输尿管软镜钬激光碎石治疗的临床资料,应用尿感宁颗粒(观察组)与未用尿感宁颗粒(对照组)进行对照分析。对照组40例采用输尿管软镜钬激光碎石术,围手术期静脉用抗生素2～3天。观察组40例采用输尿管软镜钬激光碎石术,围手术期静脉用抗生素2～3天,术后联合尿感宁颗粒治疗。术后2周复查尿常规及尿路CT平扫,评估尿路感染控制情况及结石清除率。结果 所有患者均一次性碎石成功,5例(6.25％)出现术后发热,均在术后6h内发生,最高体温在38.5℃以下,抗炎对症治疗后好转。观察组2周后结石排净率为97.50%(39/40),尿路感染治愈率97.50%(39/40)；对照组结石排净率为90.00%(36/40),尿路感染治愈率82.50%(33/40)。两组相比结石排净率有差异,但差异无显著统计学意义(P＞0.05),尿路感染治愈率差异具有显著统计学意义(P <0.05)。结论 输尿管软镜钬激光碎石术是治疗合并尿路感染肾结石的安全有效方法,术后联合应用尿感宁颗粒可提高结石清除率,尤其可明显提高尿路感染治愈率。 |
| 英文摘要: |
| Objectives To evaluate the clinical efficacy and security of flexible ureteroscopy and holmium laser lithotripsy combined with urine ganning granule in the treatment of renal calculi complicated with urinary tract infection．Methods Retrospective analysis of clinical data of 80 cases of renal calculi complicated with urinary tract infection treated with flexible ureteroscopy and holmium laser lithotripsy in our hospital between December 2018 and April 2019, a comparative analysis was conducted between urine ganning granules(the observation group) and non- urine ganning granules(the control group). In the control group,40 patients underwent flexible ureteroscopy and holmium laser lithotripsy, and intravenous antibiotics were given for 2-3 days in the perioperative period. In the observation group,40 patients were treated with flexible ureteroscopy and holmium laser lithotripsy, intravenous antibiotics were given for 2-3 days during the perioperative period, and combined with urine ganning granules after the operation. The control of urinary tract infection and rate of stone clearance were assessed by routine urinalysis and CT scan after two weeks. Results The procedures of flexible uretero- |
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