欢迎访问浙江中西医结合杂志   今天是   加入收藏   |   设为首页
任连杰,应栩华.益气养阴方联合化疗治疗ⅢB-Ⅳ期非小细胞肺癌的临床观察[J].浙江中西医结合杂志,2021,31(4):
益气养阴方联合化疗治疗ⅢB-Ⅳ期非小细胞肺癌的临床观察
Supplementing Qi and Nourishing Yin Plus Chemotherapy to Treat Patients with ⅢB-Ⅳ Non-small Cell Lung Cancer Clinical Observation
投稿时间:2020-08-03  修订日期:2021-03-09
DOI:
中文关键词:  非小细胞肺癌  益气养阴方  化学疗法
英文关键词:non-small cell lung cancer, yiqi yangyin , chemotherapy
基金项目:
作者单位E-mail
任连杰 浙江大学医学院附属金华医院传统医学中心 974494971@qq.com 
应栩华 浙江省立同德医院  
摘要点击次数: 72
全文下载次数: 0
中文摘要:
      目的:观察益气养阴方联合化疗治疗气阴两虚型ⅢB-Ⅳ期非小细胞肺癌(NSCLC)的临床疗效。方法:90例NSCLC患者按随机数字表法随机分为治疗组和对照组,各45例。对照组给予常用的非小细胞肺癌化疗方案治疗,治疗组在对照组治疗的基础上联合中药汤剂益气养阴方口服,两组疗程均为6周。观察并比较2组治疗前后瘤体大小、免疫功能指标、血常规的改变情况,并评估临床疗效。结果:两组在实体瘤疗效方面无明显差异(P>0.05)。治疗组治疗后患者CD3+、CD4+均较治疗前上升(P<0.05),并高于同期对照组患者CD3+、CD4+(P<0.05)。治疗组患者I-III度骨髓抑制发生例数均少于对照组,骨髓抑制发生率低于对照组(P<0.05)。结论:在化疗基础上加用益气养阴方能够明显提高气阴两虚型ⅢB-Ⅳ期非小细胞肺癌患者免疫功能,并减轻骨髓抑制。
英文摘要:
      Objective:To observe the clinical benefit of supplementing qi and nourishing yin combined with chemotherapy in treating III-IV NSCLC with deficiency of qi and yin. Methods: Ninety NSCLC patients were randomly divided into treatment group and control group according to the random number table method, with 45 cases in each group. The control group was treated with the first-line chemotherapy regimen. On the basis of the treatment of the control group, the treatment group combined with Chinese medicine Yiqi Yangyin prescription orally.Two groups are 6 weeks for a cycle.Observe and compare the changes of tumor size,immune function indexes, blood routine before and after treatment in the two groups, and evaluate the clinical efficacy. Results:The two groups in the evaluation of solid tumors, although no significant difference (P> 0.05). After treatment, both CD3+ and CD4+ in the treatment group were increased compared with those before treatment (P < 0.05), and were higher than those in the control group during the same period (P < 0.05). The number of patients with grade I-III bone marrow suppression in the treatment group was less than that in the control group, and the incidence of bone marrow suppression was lower than that in the control group (P<0.05). Conclusion:The addition of Yiqi Yangyin Recipe on the basis of chemotherapy can significantly improve the immune function of patients with Qi and Yin deficiency type IIIB-IV non-small cell lung cancer, and reduce bone marrow suppression.
查看全文  查看/发表评论  下载PDF阅读器
关闭