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赵春薇,倪海祥.炎症相关生物标志物对糖尿病肾病的诊断价值[J].浙江中西医结合杂志,2021,31(4):
炎症相关生物标志物对糖尿病肾病的诊断价值
投稿时间:2020-07-14  修订日期:2020-08-17
DOI:
中文关键词:  糖尿病肾病  炎症生物标志物 微量白蛋白尿
英文关键词:Diabetic  kidney disease, inflammatory  biomarkers, microalbuminuria
基金项目:
作者单位E-mail
赵春薇 浙江中医药大学第一临床医学院 1379163456@qq.com 
倪海祥 浙江中医药大学附属第一医院 haixiang1017@163.com 
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中文摘要:
      糖尿病肾脏疾病(diabetic kidney disease,DKD)为糖尿病主要微血管并发症之一,可导致终末期肾脏病,是糖尿病致死主要原因之一。尿白蛋白是诊断DKD最常用的临床指标。然而,一些DKD患者肾脏出现病变时尿白蛋白仍在正常范围。因此,寻找新的敏感而特异的生物学指标对DKD的诊断和疾病判断具有重要意义进展。近年来,与DKD发病机制相关的炎症生物标志物已逐渐成为临床研究的热点。
英文摘要:
      Diabetic kidney disease (DKD) is one of major microvascular complications of diabetes, contributing to end-stage renal disease considered as the major cause of death in diabetes. Urinary albumin is the most universal indicator of diabetic diagnosis in clinical. Nonetheless, the presence of renal lesions precedes than the abnormal level of urinary albumin in some DKD patients. Hence, it is significant to discover biomarkers of DKD diagnosis and disease identification with high sensitivity and specificity. In recent years, clinical researchers mainly focuses on exploring inflammatory biomarkers in correlation with the pathogenesis of DKD.
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