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罗 娜,李亚妤.可诱导共刺激分子及其配体与系统性红斑狼疮的研究进展[J].浙江中西医结合杂志,2021,31(2):
可诱导共刺激分子及其配体与系统性红斑狼疮的研究进展
Research progress on inducible costimulatory molecules and their ligands and systemic lupus erythematosusLuo Na Li Yayu
投稿时间:2020-07-12  修订日期:2020-09-13
DOI:
中文关键词:  可诱导共刺激分子  可诱导共刺激分子配体  系统性红斑狼疮  狼疮性肾炎
英文关键词:Inducible costimulatory molecule  inducible costimulatory molecular ligands  systemic lupus erythematosus  lupus nephritis
基金项目:
作者单位E-mail
罗 娜 浙江中医药大学附属广兴医院 2692538487@qq.com 
李亚妤* 浙江中医药大学附属广兴医院 liyayu3618@163.com 
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中文摘要:
      可诱导共刺激分子(ICOS)及其配体可诱导共刺激分子配体(ICOSL)是CD28/B7家族第三个成员,在系统性红斑狼疮的发生发展中发挥重要作用。近些年,ICOS/ICOSL在SLE的治疗方面的研究逐年深入,为临床SLE治疗提供了新思路。本文主要就ICOS/ICOSL与SLE关系进行概述。
英文摘要:
      Inducible Costimulatory Molecule (ICOS) and its ligand Inducible Costimulatory Molecule Ligand (ICOSL) is the third member of the CD28/B7 family and plays an important role in the development of systemic lupus erythematosus. In recent years, ICOS/ICOSL"s research on the treatment of SLE has been deepened year by year, providing new ideas for clinical SLE treatment. This article mainly summarizes the relationship between ICOS/ICOSL and SLE.
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