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胡慧敏.不育症男性风疹病毒感染与精子DNA碎片率的相关分析[J].浙江中西医结合杂志,2020,30(10):
不育症男性风疹病毒感染与精子DNA碎片率的相关分析
The relationship analysis of Rubella virus infection with sperm DNA fragmentation index in male infertility
投稿时间:2020-06-29  修订日期:2020-07-29
DOI:
中文关键词:  男性  不育症  风疹病毒  精子DNA碎片率
英文关键词:male infertility  Rubella virus infection  sperm DNA fragmentation index
基金项目:杭州市医药卫生科技计划项目(2016A038)
作者单位E-mail
胡慧敏 浙江省中西医结合医院 krace1982@163.com 
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中文摘要:
      目的:探讨不育症男性风疹病毒(Rubella virus)感染情况及其与精子DNA碎片率的关系。 方法:检测553例不育男性患者血清中的风疹病毒IgM抗体,将患者分为风疹病毒IgM(RV-IgM)阳性组和风疹病毒IgM(RV-IgM)阴性组,分别检测精子DNA碎片率。 结果:RV-IgM阳性组的精子DNA碎片率显著高于RV-IgM阴性组(P<0.05)。结论:风疹病毒急性感染对精子DNA完整性有影响,可能导致男性不育。
英文摘要:
      Objective: To investigate status of Rubella virus(RV)infection in male infertility,and analyze the relationship of Rubella virus infection with sperm DNA fragmentation index(DFI).Methods:Detect serum Rubella virus antibody in 553 patients of male infertility.The patients were divided into the positive group of RV-IgM and the negative group of RV-IgM.Then detect their sperm DNA fragmentation index.Results: Sperm DNA fragmentation index in the positive group of RV-IgM were significantly higher than that in the negative group of RV-IgM. Conclusion:Rubella virus recent infection can affect sperm DNA fragmentation index,it may be one reason of male infertility.
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