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王莉,丁彩飞,沈瑛红.多囊卵巢综合征育龄期妇女生活行为方式管理和干预的效果分析[J].浙江中西医结合杂志,2021,31(1):
多囊卵巢综合征育龄期妇女生活行为方式管理和干预的效果分析
Analysis on the effect of management and intervention of lifestyle in women of childbearing age with polycystic ovary syndromeWANG li, DING caifei, MA jianxiong, WANG chenye, SHEN yinghong. Department of Nephrology, Zhejiang Chinese and Western medicine hospital, Hangzhou (310003), China
投稿时间:2020-04-20  修订日期:2020-06-13
DOI:
中文关键词:  多囊卵巢综合征  育龄期妇女  生活行为方式  干预效果
英文关键词:Polycystic ovary syndrome  Women of childbearing age  Life style  Intervention effect
基金项目:浙江省基础公益研究计划(LQ19H270005);杭州市卫生计生科技计划项目(2017A40)
作者单位E-mail
王莉 浙江省中西医结合医院 WL727118@163.com 
丁彩飞 浙江省中西医结合医院  
沈瑛红* 浙江省中西医结合医院 syh163@163.com 
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中文摘要:
      目的 探讨多囊卵巢综合征(PCOS)育龄期妇女进行生活行为方式管理和干预的效果。方法 选取160例PCOS育龄期妇女,随机分为两组,对照组给予达英-35联合二甲双胍等药物治疗,观察组在药物治疗基础上,给予生活行为方式管理和干预;比较两组干预6个月后的内分泌代谢指标、性激素指标及治疗效果指标。结果 干预6个月后,观察组的FINS、TG、BMI水平均低于对照组(P<0.01);观察组的LH、LH/FSH、T水平均低于对照组(P<0.01);观察组的月经恢复率、排卵率、妊娠率分别为93.75%、76.25%及32.50%,均高于对照组的66.25%、52.50%及12.50%(P<0.05)。结论 PCOS育龄期妇女进行药物联合生活行为方式管理和干预后,可控制内分泌代谢紊乱,降低雄性激素水平,提高排卵率和妊娠率。
英文摘要:
      Objective To explore the effect of management and intervention of lifestyle in women of childbearing age with polycystic ovary syndrome (PCOS). Methods 160 cases of women of childbearing age with PCOS were chosen and randomly divided into two groups. The control group was given Diane-35 combination with Metformin, and the observation group was added management and intervention of lifestyle in the basis of medical treatment. The indexes of endocrine metabolism, sex hormone and treatment effect were compared between the two groups after 6 months intervention. Results After 6 months intervention, the levels of FINS、TG and BMI in the observation group were all lower than the control group (P<0.01). The levels of LH, LH/FSH and T in the observation group were also lower than the control group (P<0.01). But the rates of menstrual recovery, ovulation and pregnancy in the observation group were respectively 93.75%、76.25% and 32.50%, all higher than the control group (66.25%、52.50% and 12.50%, all P<0.05). Conclusion PCOS women of childbearing age after management and intervention of lifestyle, it could control endocrine and metabolic disorders, cut down androgen levels, and raise ovulation rate and pregnancy rate.
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