| 林军,宋佳音.基于现代文献的中医药防治酒精性肝炎的临床用药规律分析[J].浙江中西医结合杂志,2020,30(11): |
| 基于现代文献的中医药防治酒精性肝炎的临床用药规律分析 |
| Analysis of clinical medication of traditional Chinese medicine in the prevention and treatment of alcoholic hepatitis based on modern literature |
| 投稿时间：2020-01-13 修订日期：2020-06-29 |
| DOI： |
| 中文关键词: 酒精性肝炎 中医药 用药规律 数据挖掘 |
| 英文关键词:alcoholic hepatitis traditional Chinese medicine clinical medication data mining |
| 基金项目:温州市科技局基础性医疗卫生科技项目(Y20190720) |
|
| 摘要点击次数: 575 |
| 全文下载次数: 1 |
| 中文摘要: |
| 目的：运用数据挖掘技术分析中医药防治酒精性肝炎的临床组方用药配伍规律,为临床及科研提供思路和参考。方法：计算机检索中国生物医学文献数据库(SinoMed)、中国期刊全文数据库(CNKI)、维普中文科技期刊数据库(VIP)、万方数据库(WANFANG DATA)建库以来至2019年10月中医药防治酒精性肝炎相关文献和方剂,采用频次分析、系统聚类分析和关联规则分析的数据挖掘方法分析临床组方用药规律。结果：共纳入治疗酒精性肝炎的有效方剂31首,涉及中药95味,出现频数较高的单味药为茯苓、丹参、柴胡、山楂、茵陈等,主要药类为利水渗湿药、补虚药、清热药、活血化瘀药等。系统聚类提示将高频药物聚为8类时较好。关联分析提示的常用药对包括郁金配伍大黄,茯苓配伍白术,山楂配伍枳椇子、丹参。结论：酒精性肝炎的治疗原则以扶正祛邪、攻补兼施为主,临床多将健脾补虚药与清热利湿药、活血化瘀药、疏肝解郁药、理气化痰药同用,辅以葛花、枳椇子等解酒专药。 |
| 英文摘要: |
| Objective: To analyze clinical medication and compatibility of traditional Chinese medicine prescriptions in the prevention and treatment of alcoholic hepatitis based on data mining technology, so as to provide ideas and references for clinical and scientific research. Methods: Modern literatures of SinoMed, CNKI, VIP, WanFang DATA were searched by computer from establishment to October 2019. The data mining methods of frequency analysis, system cluster analysis and association rule analysis were used to analyze clinical medication and compatibility of prescriptions. Results: 31 effective prescriptions were included, involving 95 Chinese herbs. Chinese herbs with high frequency was Fuling, Danshen, Chaihu, Shanzha, Yinchen. The main drugs were diuretic, tonic, heat clearing, blood activating and stasis removing. It is suggested that it is better to cluster high frequency drugs into 8 groups. The commonly used medicine pairs suggested by correlation analysis include Yujin with Dahuang, Fuling with Baizhu, Shanzha with Zhijuzi and Danshen Conclusion: The therapeutic principle of alcoholic hepatitis is to strengthen the body and eliminate pathogenic factors, and tonification and purgation in combination. In clinical practice, the herbs for tonifying spleen and reinforcing deficiency are often used together with herbs for clearing heat and removing dampness, improving blood circulation and dispersing stasis, soothing liver-qi stagnation, and regulating qi-flowing for eliminating phlegm, supplemented with herbs of alcohol relieving such as Gehua and Zhijuzi. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
