| 余明军.老年急性胰腺炎临床特征及其预后相关因素的回顾性研究[J].浙江中西医结合杂志,2020,30(6): |
| 老年急性胰腺炎临床特征及其预后相关因素的回顾性研究 |
| Clinical characteristics and prognostic factors of acute pancreatitis in the elderly |
| 投稿时间：2019-11-24 修订日期：2020-02-11 |
| DOI： |
| 中文关键词: 急性胰腺炎 老年 临床资料 预后 并发症 |
| 英文关键词:acute pancreatitis elder patients clinical Characteristics prognosis complication |
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| 中文摘要: |
| 目的：分析老年急性胰腺炎患者的临床特征及影响老年急性胰腺炎患者预后的相关因素，为提高对老年急性胰腺炎患者的临床诊断和治疗水平提供依据。方法：回顾2005年5月至2018年10月期间在我院治疗的急性胰腺炎患者696例。将患者按照年龄分为老年组（≥60岁，n=365）和对照组（<60岁，n=331），比较两组患者的性别、病情分级、发病原因、住院时间、并发症、复发和死亡情况等临床资料。结果：老年组患者胆源性胰腺炎比例高于对照组。老年组患者的局部和全身并发症发生率均高于对照组患者。老年组患者的改良CT严重指数评分、开始饮食时间、住院时间及复发比例均劣于对照组。老年组患者出现腹痛和腹膜刺激征的比例低于对照组患者，而出现黄疸、胸水和腹水等临床症状的比例高于对照组患者。老年组患者器官功能障碍的发生率高于对照组患者，老年组死亡及复发率较对照组高。结论：老年急性胰腺炎以胆源性胰腺炎导致最为常见，并发症发生率高，且更易复发，预后更差。临床工作中应密切关注老年急性胰腺炎患者的血液学检查，及时处理各种并发症。 |
| 英文摘要: |
| Abstract: Objective: To explore the clinical data in different ages and prognosis of elder patients with acute pancreatitis and to provide a basis for improving the clinical diagnosis and treatment of elderly patients with acute pancreatitis. Methods: Collected from May 2005 to October 2018 in our hospital during the period of treatment of 696 cases of patients with acute pancreatitis, the patients included in the study were divided into old age groups (≥60 years old, n=365) and control group (< 60 years old, n = 331).The gender, age, grade of disease, etiology, hospital time, complications, recurrence and death were compared between the two groups. Results: In the elderly group, the proportion of acute pancreatitis caused by biliary disease was significantly higher than that in control group. The incidence of local complications and systemic complications in the elderly group were significantly higher than that in the control group. And control group of patients with CT severity index scores improved, start eating time, length of hospital stay, and recurrence rate were significantly better than patients with elderly group. The incidence of abdominal pain and peritoneal irritation in elderly group were significantly lower than the proportion of the young and middle-aged group of patients, the clinical symptoms such as jaundice, pleural effusion and ascites was significantly higher than the proportion of the young and middle-aged group of patients. The rate of organ dysfunction in elderly patients was significantly higher than that in the middle-aged and young patients. Conclusion: Elderly acute pancreatitis resulted from gallstone pancreatitis is the most common, high incidence of complications, and are more likely to relapse, so for elderly patients with acute pancreatitis should give timely and effective diagnosis and treatment, improve the prognosis of elderly patients with acute pancreatitis. |
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