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黄鸯鸯.消癌平胶囊联合化疗用于晚期食管癌治疗的临床分析[J].浙江中西医结合杂志,2020,30(5):
消癌平胶囊联合化疗用于晚期食管癌治疗的临床分析
Clinical Analysis of Xiaoaiping Capsule Combined with Chemotherapy in the Treatment of Advanced Esophageal CarcinomaHuang Yang Yang 1Zhang JuanJuan 1 Xiao HanLu1 Wu ZhongPing2 Jinhua dew fall wild goose Guangfu Hospital of the1 Department of Gastroenterology2 321000
投稿时间:2019-10-24  修订日期:2020-04-22
DOI:
中文关键词:  消癌平胶囊  化疗  晚期食管癌
英文关键词:Xiaoaiping capsule  chemotherapy  advanced esophageal cancer
基金项目:
作者单位E-mail
黄鸯鸯 金华广福医院 huangyangyangzzx@163.com 
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中文摘要:
      目的 探讨消癌平胶囊联合化疗用于晚期食管癌治疗的临床差异。方法 选取近期来我院住院治疗的晚期食管癌患者作为观察对象,随机分为两组,对照组予以常规化疗,观察组采取消癌平联合化疗共同治疗,比较2组患者治疗后临床疗效、肿瘤标志物及生活质量改善情况的差异。结果 观察组临床缓解率为70.0%,显著高于对照组的临床缓解率40.0%,差异有统计学意义(p<0.05)。2组患者治疗后CA199、CEA、SCC-Ag、CYFRA21-1水平显著降低,较治疗前差异有统计学意义(p<0.05),其中观察组较对照组在治疗后CA199、CEA、SCC-Ag、CYFRA21-1水平下降更为显著,差异有统计学意义(p<0.05)。观察组较对照组在治疗后,食欲改善、哽咽改善及KPS评分提高更为显著,差异有统计学意义(p<0.05)。结论 消癌平胶囊联合化疗用于晚期食管癌患者,能够显著改善患者临床疗效,改善患者生活质量,值得进一步深究。
英文摘要:
      Objective To investigate the clinical differences between Xiaoaiping Capsule combined with chemotherapy in the treatment of advanced esophageal cancer. Methods Patients with advanced esophageal cancer who were recently hospitalized in our hospital were randomly divided into two groups. The control group received conventional chemotherapy. The observation group was treated with Xiaoaiping combined with chemotherapy. The clinical efficacy and tumor markers of the two groups were compared. Differences in the improvement of quality of life and quality of life. Results The clinical remission rate of the observation group was 70.0%, which was significantly higher than that of the control group (40.0%). The difference was statistically significant (p<0.05). The levels of CA199, CEA, SCC-Ag and CYFRA21-1 were significantly lower in the two groups after treatment, which was statistically significant (p<0.05). The observation group was compared with the control group after treatment with CA199, CEA and SCC-Ag. The level of CYFRA21-1 decreased more significantly, and the difference was statistically significant (p<0.05). Compared with the control group, the improvement of appetite, improvement of pharynx and KPS score were more significant in the observation group than in the control group, and the difference was statistically significant (p<0.05). Conclusion Xiaoaiping Capsule combined with chemotherapy for patients with advanced esophageal cancer can significantly improve the clinical efficacy of patients and improve their quality of life. It is worth further study.
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