| 庄永卫,张剑美,朱雅碧,叶淑芳,陈军贤.经皮内镜下胃或空肠造瘘术治疗肠道功能衰竭患者的临床意义[J].浙江中西医结合杂志,2020,30(2): |
| 经皮内镜下胃或空肠造瘘术治疗肠道功能衰竭患者的临床意义 |
| Clinical Significance of Percutaneous Endoscopic Gastrostomy or Percutaneous Endoscopic Jejunostomy in Treatment of Patients with Intestinal Failure |
| 投稿时间：2019-09-06 修订日期：2019-12-11 |
| DOI： |
| 中文关键词: 鼻饲 肠内营养 肠道功能衰竭 经皮内镜下胃或空肠造瘘术 |
| 英文关键词:Nasal feeding Enteral nutrition Intestinal failure Percutaneous Endoscopic Gastrostomy or Percutaneous Endoscopic Jejunostomy |
| 基金项目:浙江省科技计划项目（2014F50031）；浙江省医药卫生科技计划项目（2A21420） |
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| 中文摘要: |
| 目的 评估经皮内镜下胃或空肠造瘘术对肠道功能衰竭患者进行胃肠内营养支持后一些临床指标的变化的研究价值。方法74例肠功能衰竭患者按随机数表法分为造瘘组37例和鼻饲组37例，造瘘组接受内镜下胃或空肠造瘘术后进行胃肠内营养支持，鼻饲组经鼻胃管进行胃肠内营养支持并且治疗14天，最后比较两组患者血红蛋白、血清白蛋白、C反应蛋白、胃肠道功能评分和便血等指标变化，以及对比两组不良反应发生情况。结果 治疗后造瘘组的便血、胃肠道功能评分及血清白蛋白指标明显优于鼻饲组，差异均有统计学意义(P<0.05)，而血红蛋白、C反应蛋白变化与鼻饲组相比差异无明显统计学意义(P>0.05)，两组患者恶心呕吐、腹胀、腹泻不良反应发生情况相比差异无明显统计学意义(P>0.05)。结论 在临床应用中内镜下胃或空肠造瘘术行胃肠内营养支持对改善肠功能衰竭患者营养状况，尤其在提升血清白蛋白，减少患者便血情况及提升患者胃肠道功能具有一定的优势。 |
| 英文摘要: |
| Objective To evaluate the research value of changes of some clinical indicators after percutaneous endoscopic gastrostomy or jejunostomy for patients with intestinal failure supported by enternal nutrition. Methods 74 patients with intestinal failure were divided into ostomy group (n = 37) and nasogastric feeding group (n = 37) according to random number table method. The ostomy group received enternal nutrition support after endoscopic gastrostomy or jejunostomy, while the nasogastric feeding group received enternal nutrition support via nasogastric tube and was treated for 14 days. Finally, the changes of hemoglobin, serum albumin, C-reactive protein, gastrointestinal function score and hematochezia and other indexes of the two groups were compared, and the occurrence of adverse reactions were compared. Results After treatment, the score of hematochezia, gastrointestinal function and serum albumin in colostomy group were significantly better than those in nasogastric feeding group, the difference was statistically significant (P<0.05), while the changes of hemoglobin and c-reactive protein had no significant difference compared with nasogastric feeding group (P>0.05). there was no significant difference in adverse reactions of nausea, vomiting, abdominal distension and diarrhea between the two groups (P>0.05). Conclusions In clinical application, endoscopic gastrostomy or jejunostomy with enternal nutrition support has certain advantages in improving the nutritional status of patients with intestinal failure, especially in increasing serum albumin, reducing hematochezia and improving gastrointestinal function of patients. |
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