| 郑仁智,高雁婷,李晓蕾,魏 岳,叶宝东,沈一平.基于数据挖掘的周郁鸿治疗再生障碍性贫血用药规律研究[J].浙江中西医结合杂志,2020,30(3): |
| 基于数据挖掘的周郁鸿治疗再生障碍性贫血用药规律研究 |
| Analysis on Zhou Yu-hong’s medication rule of prescriptions in treating aplastic anemia based on date mining |
| 投稿时间：2019-04-14 修订日期：2019-12-27 |
| DOI： |
| 中文关键词: 贫血 再生障碍性 周郁鸿 名医经验 数据挖掘 |
| 英文关键词:Anemia, Aplastic, Famous doctor’s experience, Zhou Yu-hong, data mining |
| 基金项目: |
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| 摘要点击次数: 668 |
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| 中文摘要: |
| 本研究应用数据挖掘方法，分析和总结周郁鸿治疗再生障碍性贫血的组方规律及用药特色。本研究收集了2015年09月-2017年10月期间，周郁鸿治疗再生障碍性贫血患者的中药处方数据，采用频数分析、聚类分析及复杂网络分析等数据挖掘方法分析其处方用药规律，共纳入1667则处方，中药共229味，频率＞15%的高频中药33味，演化得出6类新处方，3个核心配伍。本研究验证了周郁鸿治疗再生障碍性贫血以填精益髓结合健脾调中为主，佐以固脱止血或凉血止血的组方思路；并且进一步提出了补骨脂与菟丝子配伍益髓补劳治本，茯苓与当归配伍防治痰瘀之变的新理论。 |
| 英文摘要: |
| The data mining method was used to analyze and summarize the prescription regularities and drug administering characteristics of Zhou Yu-hong in the treatment of aplastic anemia. Datas of prescriptions of aplastic anemia treated by ZhouYu-hong were collected from Sep 2015 to Oct 2017. The data mining medehods, such as Frequency analysis, cluster analysis, and complex network analysis, were used to analyze the prescription regularity of aplastic anemia. 1667 prescriptions were included, involving 299 herbs, in which 33 herbs have a higher frequency of more than 15% ; after evolution, 6 new prescriptions and 3 core compatibilities were obtained. This study verified Zhou Yu-hong’s prescription thinking of replenishing essence and nourishing marrow combine invigorating the spleen and regulating Middle-Jiao, with solidifing collapse and hemostasis or cooling blood and hemostasis. This research?also?puts forward a new theory that the compatibility of Dodder and Psoralea fruit is for essential treatment with nourishing marrow and supplement of fatigue, and the compatibility of Poria and Angelica is for prevention altered syndromes of phlegm and blood stasis. |
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