| 应丽洁.阴道支原体、衣原体与子宫颈高危型HPV感染及转归的相关性应丽洁[J].浙江中西医结合杂志,2019,29(8): |
| 阴道支原体、衣原体与子宫颈高危型HPV感染及转归的相关性应丽洁 |
| Correlation between Mycoplasma vagina and Chlamydia trachomatis and cervical high-risk HPV infection and prognosis |
| 投稿时间：2018-11-24 修订日期：2019-07-10 |
| DOI： |
| 中文关键词: 阴道支原体,衣原体,宫颈癌,高危型HPV |
| 英文关键词:Mycoplasma vaginae,Chlamydia,Cervical cancer,High-risk HPV |
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| 中文摘要: |
| 目的：随诊宫颈筛查及分泌物检查的普及,越来越多的无症状宫颈癌被发现,此次研究阴道支原体、衣原体与子宫颈高危型HPV感染及转归的相关性。选择2008年02月-2018年2月就诊于我院妇科且病理学诊断为宫颈癌者200例为观察组,选取同期我院就诊仅有宫颈黏膜慢性炎症患者150例作为对照组,比较两组HPV、HR-HPV感染率,研究宫颈癌患者 HR-HPV感染与支原体、衣原体感染的关系,探讨HR-HPV感染与支原体、衣原体感染的相关性。研究结果：1. 观察组HPV(+)感染率(99%)、HR-HPV(+)感染率(95%)均明显高于对照组(P＜0.05)。2. 阴道支原体(36.14%)、衣原体(47.22%)感染阳性率在HR-HPV感染阳性患者中发病率均高于HPV(-)患者(P＜0.05)。3. 女性生殖道中衣原体、支原体感染会增加HR-HPV感染患病率(P＜0.05)。结论：宫颈癌HR-HPV阳性患者阴道衣原体、支原体感染率明显增高,阴道衣原体、支原体为HR-HPV感染的高危因素。 |
| 英文摘要: |
| Objective:To study on the relationship between Mycoplasma vagina and chlamydia and cervical high-risk HPV infection and prognosis.Methods: 200cases of cervical cancer diagnosed in Department of gynaecology in our hospital in February 2008 to February 2018 and 150 cases of chronic inflammation of cervix mucosa at the same time as the control group were selected as the control group.Comparison of two groups of HPV and HR-HPV infection rates.Objective to study the relationship between HR-HPV infection and Mycoplasma and Chlamydia infection in patients with cervical cancer and to explore the correlation between HR-HPV infection and Mycoplasma and Chlamydia infection.Results:1.The HPV (+) infection rate (99%) and HR-HPV (+) infection rate (95%) in the observation group were significantly higher than those in the control group (P < 0.05).2. The positive rates of mycoplasma infection (36.14%) and Chlamydia (47.22%) were higher in HR-HPV positive patients than those in HPV (-) patients (P < 0.05).3. Chlamydia and mycoplasma infection in female genital tract will increase the prevalence of HR-HPV infection (P < 0.05).Conclusion:The infection rate of Chlamydia and Mycoplasma in patients with HR-HPV positive cervical cancer was significantly higher. Chlamydia vagina and Mycoplasma were high risk factors of HR-HPV infection. |
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