| 陈宗相.氨甲环酸对老年股骨转子间骨折患者效果观察及对术后失血量的影响[J].浙江中西医结合杂志,2019,29(3): |
| 氨甲环酸对老年股骨转子间骨折患者效果观察及对术后失血量的影响 |
| Effect of tranexamic acid on elderly patients with intertrochanteric fracture and its effect on postoperative blood lossChen Zongxiang,Yang Xiao bin, Chen Yuan, Jinhua People"s Hospital, Emergency surgery 321000 |
| 投稿时间：2018-06-24 修订日期：2018-09-16 |
| DOI： |
| 中文关键词: 氨甲环酸 老年股骨转子间骨折 效果 术后失血量 |
| 英文关键词:tranexamic acid femoral intertrochanteric fracture in the elderly effect postoperative blood loss |
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| 中文摘要: |
| 目的：探讨氨甲环酸对老年股骨转子间骨折患者效果观察及对术后失血量的影响。方法：选自我院于2016年2月至2018年2月期间收治的老年股骨转子间骨折患者83例作为研究对象,按照随机表法将纳入的83例患者随机分为观察组43例与对照组40例。两组患者均采用骨近端髓内钉固定术治疗。对照组于切皮前10min给予生理盐水混合液,静脉滴注；观察组于切皮前10min给予氨甲环酸,静脉滴注。两组于5d后检测术后失血量。比较两组手术时间、血红蛋白丢失量、住院时间、骨折愈合时间、术后失血量,及术前和术后3个月Harris评分变化。结果：两组手术时间比较无统计学差异(P>0.05)；观察组血红蛋白丢失量低于对照组,且有统计学差异(P<0.05)。观察组住院时间短于对照组,而骨折愈合时间快于对照组,且有统计学差异(P<0.05)。两组术后显性失血量比较无统计学差异(P>0.05)；观察组术后隐性失血量和总失血量少于对照组,且有统计学差异(P<0.05)。两组术后3个月Harris评分较术前增加,且有统计学差异(P<0.05)；观察组术后3个月Harris评分高于对照组,且有统计学差异(P<0.05)。结论：氨甲环酸对老年股骨转子间骨折患者效果明显,可明显减少术后失血量,具有重要临床研究价值。 |
| 英文摘要: |
| Objective: To investigate the effect of tranexamic acid on elderly patients with intertrochanteric fracture and the effect on blood loss after operation. Methods: the femur in the elderly from our hospital during the period from February 2016 to February 2018 were in patients with intertrochanteric fracture in 83 cases as the research object, randomly 83 patients were randomly divided into the observation group 43 cases and control group of 40 cases. Two groups of patients were treated with proximal femoral nail fixation. The control group was given 10min saline solution before skin incision and intravenous drip. The observation group was given 10min tranexamic acid and intravenous drip before skin incision. After 5D, blood loss was detected in the two groups. Compare two groups of operation time, hemoglobin loss, hospitalization time, healing time, postoperative blood loss fracture, changes in 3 months and Harris score before and after surgery. Results: no significant differences between the two groups in operation time (P>0.05); observation group hemoglobin loss is lower than the control group (P<0.05). The hospitalization time in the observation group was shorter than that in the control group, while the healing time in the observation group was faster than that in the control group (P<0.05). Two groups of postoperative visible blood loss showed no significant difference (P>0.05); the observation group postoperative recessive blood loss and total blood loss less than the control group (P<0.05). The two group after 3 months compared with preoperative Harris score increased (P<0.05); the observation group after 3 months Harris score higher than the control group (P<0.05). Conclusion: tranexamic acid is effective in the treatment of elderly patients with intertrochanteric fractures. It can significantly reduce postoperative blood loss and has important clinical value. |
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