| 郑宋宋,徐亚青,周玉琴,姬琳,牟新.糖尿病肾病合并抑郁的危险因素分析[J].浙江中西医结合杂志,2018,28(10): |
| 糖尿病肾病合并抑郁的危险因素分析 |
| Analysis of the risk factors of diabetic nephropathy with depression |
| 投稿时间：2018-03-09 修订日期：2018-04-29 |
| DOI： |
| 中文关键词: 糖尿病肾病 情绪 抑郁 危险因素 回归分析 |
| 英文关键词:Diabetic nephropathy emotion depression risk factors regression analysis |
| 基金项目:国家自然科学基金资助项目(No.81273623,No.81774217)；浙江省中医药科技计划项目(No.2016ZB094) |
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| 中文摘要: |
| 【】目的：探究糖尿病肾病合并抑郁的相关危险因素,为糖尿病肾病合并抑郁患者的临床干预提供一定的参考依据。方法：选择2016 年4月至2017年4月我院收治的糖尿病肾病患者170例,收集患者的各项临床资料,包括一般资料(性别、年龄等)、营养状态、社会支持情况等进行多因素回归分析,筛选相关的危险因素。结果：不同性别患者之间存在明显的差异,男性患者合并抑郁的比例显著低于女性患者,同时,营养不良患者合并抑郁比例显著高于营养状态良好的患者,社会支持较好的患者与社会支持较差的患者以及不同病程、不同年龄的患者、不同月收入水平、糖尿病肾病分期患者在合并抑郁比例方面也存在明显差异,(均P＜0.05),不同文化程度的患者在合并抑郁比例方面经比较差异无统计学意义,(均P＞0.05)；合并抑郁患者的平均糖化血红蛋白、空腹血糖水平均显著高于未合并抑郁患者(均P＜0.05),但合并抑郁与未合并抑郁患者的空腹胰岛素水平无明显差异,(P＞0.05)。经多因素回归分析,糖尿病肾病合并抑郁的危险因素包括性别、社会支持情况以及病程和营养状态、月收入水平,均P＜0.05。结论：糖尿病肾病患者会出现一定的合并抑郁的情况,相关的危险因素主要包括性别、社会支持情况以及病程和营养状态。临床需要针对相关的危险因素做好相应的针对性干预,以尽可能的改善患者的心理状态,减少抑郁的出现。 |
| 英文摘要: |
| objective: To explore the related risk factors of diabetic nephropathy combined with depression, and to provide some reference for the clinical intervention of diabetic nephropathy with depression.Method：170 patients with diabetic nephropathy complicated with depression from April 2016 to April 2017 in our hospital, the clinical data were collected, including general information (gender, age), multi factor regression analysis of nutritional status, social support, screening related risk factors. Result: There are obvious differences between different sex patients, male patients with depression was significantly lower than female patients, at the same time, malnutrition in patients with depression was significantly higher than the proportion of patients with good nutritional status, social support and social support in patients with poor good patients and different course, different age groups and different income level, diabetic nephropathy in patients with depression stage ratio varied significantly, (P < 0.05), different cultural levels in patients with depression by the proportion of no significant differences (P > 0.05); patients with depression average HbA1c, fasting blood glucose levels were significantly higher than patients without depression (P < 0.05), but not associated with patients with depression and fasting insulin level in patients with depression had no significant difference (P > 0.05).Multivariate regression analysis showed that the risk factors for diabetic nephropathy combined with depression included gender, social support, duration and nutritional status, and monthly income level, all P < 0.05.Conclusion: Patients with diabetic nephropathy will have a certain degree of depression. The related risk factors include gender, social support, course of disease and nutritional status.Clinical need to do pertinent intervention in response to related risk factors in order to improve the psychological state of the patients as much as possible and reduce the occurrence of depression. |
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