| 符凌辉,余佳薇.结核分枝杆菌感染控制在结核病预防中的作用分析[J].浙江中西医结合杂志,2018,28(11): |
| 结核分枝杆菌感染控制在结核病预防中的作用分析 |
| Analysis on effect of Mycobacterium tuberculosis infection control on tuberculosis prevention |
| 投稿时间：2018-01-19 修订日期：2018-05-07 |
| DOI： |
| 中文关键词: 结核病 结核分枝杆菌 感染 控制 预防 |
| 英文关键词:Tuberculosis Mycobacterium tuberculosis infection control prevention |
| 基金项目: |
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| 摘要点击次数: 783 |
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| 中文摘要: |
| 目的 探讨和分析结核分枝杆菌感染控制在结核病预防中的临床应用价值。方法 选择2014年6月～2016年6月期间医院所分离的168株结核分枝杆菌作为临床研究对象,并分别对本研究中结核分枝杆菌的来源情况和耐药情况进行统计和分析,并由此制定相应的感染控制措施。结果 168株结核分枝杆菌来源于痰液132株,占78.57%(132/168)；胸腹水21株,占12.50%(21/168)；血液9株,占5.36%(9/168)；尿液6株,占3.57%(6/168)。168株结核分枝杆菌对抗结核药物均敏感的101株,占率60.12%(101/168),对抗结核药物耐药的67株,占率39.88%(67/168)。结核分枝杆菌对异烟肼32.74%(55/168)、利福平30.36%(51/168)单药耐药的比率,以及对异烟肼+利福平24.40%(41/168)耐多药的比率均呈现出较高的耐药率,耐药率均处于20%以上。结论 加强对结核分枝杆菌来源及耐药情况的监测,并采取针对性的控制措施对于结核病的预防意义深远而重大。 |
| 英文摘要: |
| Objective: To probe into application value of Mycobacterium tuberculosis infection control on tuberculosis prevention. Methods: From June 2014 ~ June 2016, 168 strains of Mycobacterium tuberculosis were separated in our hospital as clinical study. The source and resistance situation of Mycobacterium tuberculosis were analyzed and analyzed. And to develop appropriate infection control measures. Results: In 168 strains of Mycobacterium tuberculosis, 132 cases from sputum, accounting for 78.57% (132/168); 21 cases from pleural effusion, accounting for 12.50% (21/168); 9 case from blood, accounting for 5.36% (9/168); 6 case from urine, accounting for 3.57% (6/168). In 168 strains of Mycobacterium tuberculosis, there were 101 strains susceptible to tuberculosis drugs, accounting for 60.12% (101/168), 67 strains resistant to tuberculosis drug resistance, accounting for 39.88% (67/168). The single drug resistance ratio of Mycobacterium tuberculosis to isoniazid was 32.74% (55/168), rifampicin was 30.36% (51/168), and the multidrug resistance ratio to isoniazid + rifampicin was 24.40% (41/168), showed higher resistance rate, resistance rates were more than 20%. Conclusions: Strengthen the monitoring of Mycobacterium tuberculosis source situation and drug resistance. Targeted control measures are far-reaching and significant for the prevention of tuberculosis. |
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