| 徐道芬,胡欣欣,高楚楚,孙云.抑亢汤治疗肝经湿热型多囊卵巢综合征不孕的临床观察[J].浙江中西医结合杂志,2018,28(6): |
| 抑亢汤治疗肝经湿热型多囊卵巢综合征不孕的临床观察 |
| Clinical Observation on Yikang Soup in Treatment of dampness - heat liver type Polycystic Ovary Syndrome Infertility |
| 投稿时间：2017-11-17 修订日期：2017-12-17 |
| DOI： |
| 中文关键词: 多囊卵巢综合征 不孕症 肝经湿热型 抑亢汤 子宫内膜容受性 临床观察 |
| 英文关键词:polycystic ovary syndrome infertility dampness - heat liver type Yikang soup uterine receptivity Clinical observation |
| 基金项目:浙江省中医药科技计划项(项目编号2016ZA182) |
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| 中文摘要: |
| 目的：观察抑亢汤治疗肝经湿热型多囊卵巢综合征不孕的临床疗效,初步评价其作用机理。方法：将门诊60例肝经湿热型PCOS不孕症患者随机分为研究组30例和对照组30例,月经第5天开始研究组口服克罗米芬片,连服5天,另加口服抑亢汤,连服21天；对照组口服克罗米芬片,连服5天,1个月经周期为1个疗程,共治疗6个疗程,比较治疗后排卵率及临床妊娠率,比较治疗前后生殖性激素水平情况,观察治疗后两组患者黄体期子宫动脉血流情况及子宫内膜厚度。结果：治疗后研究组的排卵率与对照组无明显差异(P>0.05),但妊娠率明显高于对照组(P<0.05)；治疗后研究组对性激素水平的改善明显优于对照组(P<0.05)；治疗后研究组的黄体期子宫动脉参数及子宫内膜厚度明显优于对照组(P<0.05)。 |
| 英文摘要: |
| Objective:Clinical effect of observing Yikang soup treats dampness - heat liver type polycystic ovary syndrome infertility, preliminary evaluation for its mechanism of action.Method: Divided outpatient 60 cases dampness - heat liver type PCOS infertility patients into research group for 30 cases and control group for 30 cases randomly, at the fifth day of menstruation, research group began oral taking clomiphene for constant 5 days, in addition with oral taking Yikang soup for 21 days; and control group oral took clomiohene for constant 5 days, one menstrual cycle is a course of treatment, and total treatment for 6 courses, compared ovulation rate and clinical pregnancy rate after treatment, and also contrasted reproductive sex hormone levels before and after treatment, observing uterine artery blood flow and endometrial thickness in luteal phase after treatment. Results : After treatment, the ovulation rate in the study group was not significantly different from that in the control group(P>0.05, but the pregnancy rate was significantly higher than that of the control group(P<0.05: The improvement of sex hormone level in the study group was better than that in the control group ( p < 0.05 ). The parameters of uterine artery and endometrial thickness in the luteal phase of the study group were significantly better than those in the control group ( p < 0.05 ). Conclusion: Yikang soup can improve the reproductive sex hormone level for dampness - heat liver type in patients with polycystic ovary syndrome, promotes ovulation, meantime increases uterine artery blood flow, improves the endometrial receptivity, improves the pregnancy rate, and is worth promoting . |
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