| 郑翔,王必铭,卢敬利.舒芬太尼联合七氟烷吸入麻醉在经胸非体外循环先心介入封堵术的效果分析[J].浙江中西医结合杂志,2018,28(10): |
| 舒芬太尼联合七氟烷吸入麻醉在经胸非体外循环先心介入封堵术的效果分析 |
| Effect of inhalation anesthesia with sufentanil and sevoflurane in transthoracic off-pump interventional occlusion for congenital heart disease |
| 投稿时间：2017-11-15 修订日期：2018-02-05 |
| DOI： |
| 中文关键词: 经胸非体外循环先心介入封堵术 舒芬太尼 七氟烷 全凭静脉麻醉 |
| 英文关键词:transthoracic non-cardiopulmonary bypass interventional occlusion for congenital heart disease sufentanil sevoflurane total intravenous anesthesia |
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| 中文摘要: |
| [摘要]目的：探讨舒芬太尼联合七氟烷吸入麻醉在经胸非体外循环先心介入封堵术的效果。方法：选取2015年1月至2017年1月本院收治的82例经胸非体外循环先心介入封堵术患者作为研究对象，随机分成两组：全凭静脉麻醉组（对照组，41例），舒芬太尼联合七氟烷组（观察组，41例）。两组患者均应用0.5μg/kg舒芬太尼，0.1mg/kg咪达唑仑，2.5mg/kg丙泊酚，0.5mg/kg阿曲库铵常规诱导。比较两组麻醉诱导前、麻醉诱导后1min、手术前及手术结束时的生命体征，手术前即刻、插管后即刻及术毕即刻的脑电双频指数(BIS)，舒芬太尼用量、麻醉恢复期情况及不良反应发生情况。结果：两组麻醉诱导前即刻、麻醉诱导后1min、手术前即刻及术毕即刻的收缩压、舒张压、心率均较为稳定，差异不显著；两组手术前即刻、插管后即刻及术毕即刻的BIS差异不显著；观察组舒芬太尼用量少于对照组，苏醒时间、拔管时间、复苏室停留时间均短于对照组，躁动评分低于对照组，差异显著(P＜0.05)；两组患者均未发生严重不良反应。结论：舒芬太尼联合七氟烷吸入麻醉在经胸非体外循环先心介入封堵术的麻醉效果满意，并且复苏迅速。
关键词：经胸非体外循环先心介入封堵术；舒芬太尼；七氟烷；全凭静脉麻醉 |
| 英文摘要: |
| Objective: To explore the effect of inhalation anesthesia with sufentanil and sevoflurane in transthoracic off-pump interventional occlusion for congenital heart disease. Methods: 82 cases with transthoracic off-pump interventional occlusion for congenital heart disease were selected as subjects from January 2015 to January 2017. These patients were randomly divided into two groups: total intravenous anesthesia (control group, 41 cases) and ufentanil combined with sevoflurane group (observation group, 41 cases). The anesthesia was induced with 0.5μg/kg ufentanil, 0.1mg/kg midazolam, 4.0mg/kg propofol, and 0.5mg/kg atracurium. The vital signs were compared between two groups before anesthesia induction, at 1 min after anesthesia induction, before surgery and after operation. The bispectral index (BIS), the dosage of sufentanil, recovery of anesthesia and adverse effect were compared between two groups before surgery, at the time of intubation and at end of operation. Results: There was no significant difference for systolic blood pressure, diastolic blood pressure and heart rate between two groups before anesthesia induction, at 1 min after anesthesia induction, before surgery and after operation. There was no significant difference for BIS before surgery, at the time of intubation and at end of operation. The dosage of sufentanil,awakening time, extubation time, stay time in recovery room and agitation score in observation group were lower than those in control group before surgery, at the time of intubation and at end of operation (P<0.05)。There was no serious adverse reactions in two groups. Conclusion: The effects of sufentanil combined with sevoflurane for transthoracic off-pump interventional occlusion for congenital heart disease are excellent and the recovery is quick. |
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