| 翟利锋,马苟平,黄凯,张春,刘亦杨.富血小板血浆关节腔注射联合穴位注射治疗膝骨性关节临床研究[J].浙江中西医结合杂志,2018,28(10): |
| 富血小板血浆关节腔注射联合穴位注射治疗膝骨性关节临床研究 |
| Clinical research of platelet-rich plasma(PRP) intra-articular injection combining with point injection therapy in treatment of knee osteoarthritisZhai Li-feng, Ma Gou-ping, Huang kai. Department of Orthepaedics, Tongde Hospital Of Zhejiang Province, Hangzhou 310012 China |
| 投稿时间：2017-09-08 修订日期：2018-01-18 |
| DOI： |
| 中文关键词: 膝,骨性关节炎,富血小板血浆,关节腔注射,穴位疗法 |
| 英文关键词:Knee Osteoarthritis PRP intra-articular injection point injection |
| 基金项目:浙江省中医药管理局基金 |
|
| 摘要点击次数: 1042 |
| 全文下载次数: 2 |
| 中文摘要: |
| 目的：探讨自体富血小板血浆（PRP）关节腔注射联合穴位注射治疗膝骨性关节炎的方法和疗效。
方法：选取2015年6月至2016年6月在我院骨科就诊的60例膝骨关节炎患者为研究对象，将其随机分为观察组（联合注射组）和对照组（关节注射组），每组各30例。观察组应用PRP关节腔注射联合穴位注射治疗，对照组采用PRP关节腔注射治疗。分别采用安大略西部和麦克马斯特大学骨关节炎指数（WOMAC）评分系统和《中医病症诊断疗效标准》中关于骨痹的疗效判定标准对两组患者在治疗前后的膝关节功能进行评价。
结果：两组患者均无严重并发症发生，治疗前后两组WOMAC评分均得到明显改善（Ｐ＜0.05）。治疗后３个月和6个月，两组间WOMAC评分比较无统计学差异（Ｐ＞0.05），治疗后12个月，两组间WOMAC评分比较显示观察组膝关节功能改善更佳，两者差异有统计学意义（Ｐ＜0.05）。根据《中医病症诊断疗效标准》中关于骨痹的疗效判定标准，对治疗后12个月两组患者的膝关节功能进行评价，观察组总有效率为93．33％。对照组总有效率为76．67％，观察组总有效率优于对照组，但两者差异尚不具有统计学意义(Ｐ＞0.05)。
结论：富血小板血浆关节腔注射联合穴位注射与关节腔注射均能改善膝骨性关节炎临床症状，但联合注射较关节腔注射获得了更持久的疗效，是一种治疗膝骨性关节炎的有效方法。 |
| 英文摘要: |
| Objective To explore the methods and efficacy of platelet-rich plasma (PRP) intra-articular injection combining with point injection therapy in patients with knee osteoarthritis(KOA).
Methods 60 patients with KOA were divided into two groups randomly in our department from June 2015 to June 2016. Each group had 30 cases. One was observation group(PRP intra-articular injection combining with point injection therapy),another was control group(PRP intra-articular injection).All cases were evaluated before and 3,6,12 months after treatment by WOMAC scores. The final efficacy were evaluated by total effective rate according to Diagnostic efficacy criteria of Chinese medicine(DECOCM).
Results No serious adverse events were detected in both groups. At the following up, both group presented a clinical improvement after treatment（P<0.05）. The comparison of WOMAC scores between the two groups showed no significant difference 3 and 6 months after treatment（P>0.05）. The WOMAC score of observation group was better than the control group 12 months after treatment(P<0.05).According to DECOCM, the total effective rate of observation group is 93.33% while the total effective rate of control group is 76.67%. The result of observation group is better, while the difference was not statistical significant（P>0.05）.
Conclusion Either PRP intra-articular injection or combining with PRP point injection can improve joint function of KOA patients, while the combination of them obtained a more lasting efficacy. PRP intra-articular injection combining with point injection therapy is a effective method for patients with KOA. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
