| 郑妮娜.维生素D水平与脑卒中后抑郁症状的相关性分析[J].浙江中西医结合杂志,2018,28(7): |
| 维生素D水平与脑卒中后抑郁症状的相关性分析 |
| Correlation between vitamin D levels and post - stroke depressive |
| 投稿时间：2017-08-16 修订日期：2018-05-18 |
| DOI： |
| 中文关键词: 脑卒中 抑郁 维生素D 相关性 |
| 英文关键词:Stroke Depression Vitamin D correlation |
| 基金项目: |
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| 中文摘要: |
| 【】目的 评价维生素D水平与脑卒中后抑郁(PSD)的相关性。方法 选择2015年3月~2016年10月在我院就诊的急性缺血性脑卒中患者134例,以发病后一个月汉密尔顿抑郁量表(HAMD)>7分为PSD组43例和非PSD组91例,再选择50例健康人群作为正常对照组,比较患者人口学病情资料、美国国立卫生研究院卒中量表(NIHSS)、Barthel指数、改良 Rankin 量表(mRS)、简易精神状态量表 (MMSE)评分和发病后24h内维生素D水平与PSD的相关性。结果 PSD组冬春发病比例高于非PSD组(P<0.05),而夏秋发病比例、NIHSS、Barthel指数、mRS、MMSE和维生素D水平低于非PSD组(P<0.05)；Logistic回归分析表明冬春季节发病、NIHSS、Barthel指数、mRS、MMSE 和维生素D水平均为PSD的危险因素(P<0.05)。结论 急性缺血性脑卒中发病后24h内维生素D水平降低与一个月内PSD发病呈正相关。 |
| 英文摘要: |
| 【】 Objective To evaluate the relationship between vitamin D levels and post-stroke depression (PSD). Methods From March 2015 to October 2016, 134 patients who were diagnosed with acute ischemic stroke in our hospital were enrolled. They were divided into PSD group (n=43) and non-PSD (n=43) by Hamilton Depression Rating Scale (HAMD) >7. The correlation between National Institutes of Health Stroke Scale (NIHSS), Barthel index, modified Rankin scale (mRS), Minimum Mental State Examination, MMSE), vitamin D level in 24 hours after onset and PSD were analyzed. Results The incidence time of winter and spring in PSD group was higher than non-PSD group (P<0.05). NIHSS, Barthel index, mRS, MMSE and vitamin D in PSD group was lower than non-PSD group (P<0.05). Logistic regression analysis showed that incidence time of winter and spring, NIHSS, Barthel index, mRS, MMSE and vitamin D were the risk factors for PSD (P<0.05). Conclusion The decrease of vitamin D level after 24 h of acute ischemic stroke is positively correlated with the incidence of PSD within one month. |
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