| 颜伟,邱萍.右美托咪定复合七氟醚对妇科腹腔镜手术全麻苏醒质量的影响[J].浙江中西医结合杂志,2018,28(7): |
| 右美托咪定复合七氟醚对妇科腹腔镜手术全麻苏醒质量的影响 |
| Effects of dexmedetomidine combined with sevoflurane on quality of the recovery from general anesthesia in patients undergoing gynecologic videolaparoscopic operation YAN Wei,QIU Ping .Department of Anesthesia , Huzhou Maternity Child Care Hospital,Huzhou 313000,China |
| 投稿时间：2017-08-07 修订日期：2018-06-14 |
| DOI： |
| 中文关键词: 右美托咪定 七氟醚 妇科 腹腔镜手术 全麻苏醒期 |
| 英文关键词:Dexmedetomidine Sevoflurane Gynaecology Videolaparoscopic operation Anesthesia recovery period |
| 基金项目: |
|
| 摘要点击次数: 714 |
| 全文下载次数: 1 |
| 中文摘要: |
| 【】目的 评价右美托咪定复合七氟醚对妇科腹腔镜手术全麻苏醒期的影响。方法 选择择期行妇科腹腔镜手术患者80例,年龄21-55岁,体重46-81kg,ASAⅠ～Ⅱ级。随机分为D组(右美托咪定联合七氟醚组)和S组(七氟醚组),每组40例。D组于麻醉诱导前10 min静脉泵注右美托咪定0.5μg/kg,S组静脉泵注生理盐水10 m1。两组诱导插管后,泵注瑞芬太尼0.05-0.2μg.kg<sub>-1</sub>.min<sub>-1</sub>,顺式阿曲库铵6-10mg/h,D组以0.2-0.5μg.kg<sub>-1</sub>.h<sub>-1</sub>持续泵注右美托咪定联合吸入3%七氟醚,S组术中持续吸入3%七氟醚维持麻醉,两组缝皮时停用麻醉药。记录两组病人一般情况,手术时间,出血量,瑞芬太尼用量,自主呼吸恢复时间,苏醒时间,拔管时间,拔管后患者的Ramsay镇静评分,躁动评分及不良反应。结果 两组患者一般情况比较无差异,D组瑞芬太尼用量明显少于S组(P<0.05),D组患者自主呼吸恢复时间、苏醒时间、拔管时间明显短于S组(P<0.05),D组拔管后患者的Ramsay镇静评分明显高于S组,呛咳发生率明显低于S组(P<0.05),躁动评分、寒战和恶心呕吐发生率比较两组无差异(P>0.05)。结论 妇科腹腔镜手术采用右美托咪定复合七氟醚全麻时,可以缩短患者苏醒时间,减少患者苏醒期的不良反应,明显提高患者全麻苏醒期质量。 |
| 英文摘要: |
| 【】 Objective To evaluate the effect of dexmedetomidine combined with sevoflurane on the quality of the recovery from general anesthesia in gynecological videolaparoscopic operation. Methods Eighty ASAⅠorⅡpatients undergoing gynecological laparoscopic surgery were equally randomized into two groups ( n= 40 each) ：group D (dexmedetomidine combined with sevoflurane group) and group S (sevoflurane group). Dexmedetomidine at 0.5μg/kg were infused over 10 min in group D before anesthesia induction, while saline was used in the group S. The two groups infusion remifentanil of 0.05-0.2μg.kg<sub>-1</sub>.h<sub>-1</sub>, cisatracurium 6-10mg/h, Inhalation of 3% sevoflurane and dexmedetomidine at 0.2-0.5μg.kg<sub>-1</sub>.h<sub>-1</sub> were infused in group D , Inhalation of 3% sevoflurane in group S for maintenance of anesthesia . Anesthetics were stopped before skin closure.Records of all of patients in general, operation time, bleeding volume, the dosage of remifentanil, spontaneous breathing recovery time, recovery time, extubation time, Ramsay sedation score, agitation score and adverse reactions.Result The general situation of the two groups had no significant difference ,Dosage of remifentanil was less in group D (P<0.05), Spontaneous breathing recovery time, recovery time, extubation time was significantly shorter in group D (P<0.05), Ramsay sedation score of group D was significantly higher than group S, the incidence of cough was lower than that in S group (P<0.05), the agitation score,the rates of chills ,nausea and vomiting had no difference (P>0.05). Conclusion Dexmedetomidine combined with sevoflurane used in general anesthesia can shorten the recovery time of patients, reduce the adverse reaction of patients during anesthesia recovery period, and improve the quality of anesthesia recovery period. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
