| 张细江.BNP在重症肺炎患者临床风险和预后估计中的意义[J].浙江中西医结合杂志,2017,27(12): |
| BNP在重症肺炎患者临床风险和预后估计中的意义 |
| Change of B-type brain natriuretic peptide in plasm o patients with severe pneumonia and its value in prognosis.Zhang xijiang, Intensive Care Unit,Taizhou municipal Hospital Affiliated to TaiZhou University.318000,China.Tai zhou |
| 投稿时间：2017-04-01 修订日期：2017-09-10 |
| DOI： |
| 中文关键词: BNP 重症肺炎 临床风险 预后 |
| 英文关键词:BNP severe pneumonia clinical condition prognosis |
| 基金项目:台州市椒江区科技局 |
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| 中文摘要: |
| 目的：探讨BNP在重症肺炎患者血浆中的变化规律,为重症肺炎患者的临床风险和预后的评估提供依据。方法：测定重症肺炎患者入院时BNP、hs-CRP水平,记录APACHEⅡ,比较其在存活、死亡患者的差异；分析重症肺炎患者BNP和APACHEⅡ/hs-CRP、氧分压的相关性；分别绘制BNP、APACHEⅡ受试者工作特征(ROC)曲线,计算曲线下面积。结果：死亡组BNP为482.00ng/l(31,1156) ,存活组BNP为216.00ng/l(26,936),明显升高,且和hs-CRP、APACHEⅡ、氧分压呈相关性；BNP预测死亡的AUC为0.745。结论：BNP可以作为重症肺炎患者临床风险、预后的评估指标。 |
| 英文摘要: |
| Objective To study the value of plasam BNP in evaluating the condition and prognosis of patients with severe pneumonia. Methods When the pneumonia patients admitted,the plasm BNP and hs-CRP level were measured,and the scores of APACHEⅡwere evaluated,then compared the differences between the survivor group and non-survivor group. The correlation between BNP and APACHE II,hs-CRP ,PO2 in patients with severe pneumonia was analyzed,and the ROC curve was constructed. Results The levels of BNP of the non-survivor group [216.00ng/l(26,936)] were higher than the survivor group [216.00ng/l(26,936)],and were related to hs-CRP, APACHEⅡ and PO2. The levels were higher than survivor group,and were related to hs-CRP, APACHEⅡ and PO2. The levels of BNP at baseline generated an area under ROC curve of 0.745.Conclusion Plasam BNP can be used to assess the condition and prognosis of patients with severe pneumonia. |
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