| 黄强,王文锐,谈健飞,陈康,叶淑菁,钱婷娴,李先东,徐文浩,张宇岚.2型糖尿病高危脑卒中风险患者中医体质学特征分析[J].浙江中西医结合杂志,2017,27(9): |
| 2型糖尿病高危脑卒中风险患者中医体质学特征分析 |
| Analysis of TCM constitution characteristics of patients with type 2 diabetes mellitus with high risk of stroke |
| 投稿时间：2017-02-05 修订日期：2017-06-30 |
| DOI： |
| 中文关键词: 2型糖尿病 高危卒中 中医体质 |
| 英文关键词:type 2 diabetes high risk of stroke TCM Constitution |
| 基金项目:浙江中医药科技项目2015ZB117；嘉善县科技项目2015A35 |
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| 中文摘要: |
| 目的 探讨2型糖尿病高危脑卒中患者主要高频体质类型间临床生理病理及多重危险因素的差异。方法 首先将630例T2DM患者按照改良的Framingham评分表筛选出卒中高危患者,参照《中医体质分类与判定》获得主要高频体质类型并进行分组,比较性别、年龄、病程、卒中概率、BMI、WHR、SBP、DBP、HbA1c、SUA、TC、TG、hs-CRP、Hcy、CIMT、颈动脉斑块等项目。结果(1)444例T2DM高危患者的主要高频体质类型是：气虚质,阴虚质,气阴两虚质,气阴两虚兼痰湿质,气阴两虚兼血瘀质。(2)气阴两虚质,气阴两虚兼痰湿质和气阴两虚兼血瘀质3组的女性比高于气虚质组；气虚质、气阴两虚兼痰湿质和气阴两虚兼血瘀质3组的年龄高于阴虚质组；气阴两虚兼血瘀质的卒中概率高于其余4组。(3)气阴两虚兼血瘀质组的吸烟率高于气虚质组、气阴两虚质组；气阴两虚兼痰湿质、气阴两虚兼血瘀质2组的TC、TG高于其他3组。(4)气阴两虚兼痰湿质,气阴两虚兼血瘀质2组的SUA高于阴虚质组；气阴两虚质、气阴两虚兼痰湿质,气阴两虚兼血瘀质3组的SUA高于气虚质组。(5)气阴两虚兼痰湿质的hs-CRP、Hcy均高于其他4组；气阴两虚兼痰湿质、气阴两虚兼血瘀质2组的CIMT、颈动脉斑块均高于其他3组；气阴两虚兼血瘀质组的CIMT高于气阴两虚兼痰湿质组。结论T2DM卒中高危患者主要高频体质依次为气虚质,阴虚质,气阴两虚质,气阴两虚兼痰湿质,气阴两虚兼血瘀质。气阴两虚兼痰湿质,气阴两虚兼血瘀质2类型有更高的卒中危险因素和颈动脉硬化的病理表现。 |
| 英文摘要: |
| Objective to investigate the differences of clinical physiology, pathology and multiple risk factors in patients with type 2 diabetes with high risk of stroke. Methods the 630 cases of T2DM patients according to the modified Framingham score were screened in patients with high risk of stroke, according to the "Chinese constitution classification and decision" for the main types of constitution and the high frequency group, gender, age, course of disease, compared with BMI, WHR, stroke probability, SBP, DBP, HbA1c, SUA, TC, TG, hs-CRP, Hcy, CIMT and carotid artery plaque project.Results (1)444 cases of T2DM patients at high risk of major high frequency physical type is Qi deficiency, yin deficiency, Qi and yin deficiency, yin deficiency and phlegm dampness, Qi and yin deficiency and blood stasis. (2) yin deficiency constitution, yin deficiency and phlegm and blood stasis of Qi Yin deficiency and 3 groups of female higher than Qi deficiency group; Qi deficiency, yin deficiency and phlegm and blood stasis of Qi Yin deficiency and 3 groups of age higher than Yin deficiency group; stroke probability of yin deficiency and blood stasis quality than the other 4 groups. (3) yin deficiency and blood stasis matter group smoking rate is higher than that of qi deficiency group and yin deficiency constitution group; Qi and yin deficiency and phlegm, Qi and yin deficiency and blood stasis group 2 TC, TG higher than the other 3 groups. (4) Qi and yin deficiency and phlegm dampness, Qi and yin deficiency and blood stasis group 2 SUA higher than Yin deficiency group; Qi quality, Qi and yin deficiency and phlegm, Qi and yin deficiency and blood stasis group 3 SUA higher than Qi deficiency group.(5) Qi and yin deficiency and phlegm dampness of hs-CRP and Hcy were higher than the other 4 groups; Qi and yin deficiency and phlegm, yin deficiency and blood stasis constitution in 2 groups of CIMT, carotid plaques were higher than the other 3 groups; Yin deficiency and blood stasis matter group CIMT higher than Qi and Yin deficiency and phlegm dampness group.conclusions The main of T2DM high frequency high risk of stroke in patients with physical Qi deficiency, yin deficiency, Qi and yin deficiency, yin deficiency and phlegm dampness, Qi and yin deficiency and blood stasis. Qi and yin deficiency and phlegm dampness, Qi and yin deficiency and blood stasis: there are 2 types of pathological manifestations of higher stroke risk factors and carotid atherosclerosis. |
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