| 张江松,林咸明.以太冲为主穴的不同经穴配伍针刺对SHR大鼠血压调节效应的比较[J].浙江中西医结合杂志,2017,27(8): |
| 以太冲为主穴的不同经穴配伍针刺对SHR大鼠血压调节效应的比较 |
| Comparison of Anti-hypertension Effect of Selecting Taichong (LR3) as the Major Point plus different acupoints of acupuncture on Rats with Spontaneous HypertensionZHANG Jiang-song,YANG Ya-yuan,CHEN Yue-ting,XIAO Shuang-kai,JIAO Jun-yue,LIN Xian-ming |
| 投稿时间：2016-12-29 修订日期：2017-04-24 |
| DOI： |
| 中文关键词: 自发性高血压大鼠 血压 太冲 配穴 针刺 |
| 英文关键词:SHR Blood pressure LR3 Acupoint compatibility Acupuncture |
| 基金项目:国家重点基础研究发展计划（973计划） |
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| 中文摘要: |
| 目的 观察以太冲为主穴的不同经穴配伍针刺对自发性高血压大鼠(SHR)血压的调节效应，探讨不同经穴配伍对经穴效应的影响。方法 将96只SHR大鼠分为模型组、非穴组、太冲组、内关组、太溪组、蠡沟组、光明组、太冲配非穴组、太冲配内关组、太冲配太溪组、太冲配蠡沟组和太冲配光明组，共12组，每组8只。毫针刺入穴位后，留针30min，每日1次，连续15次；模型组同法固定不予针刺。各组大鼠分别在针刺前以及针刺15天后，采用大鼠尾动脉无创测量法测量收缩压（SBP）、舒张压（DBP）。结果 针刺15天后，太冲配内关组SBP（192.52±6.76）低于太冲组（209.48 ±6.94）和内关组（208.98 ±5.30）；太冲配内关组DBP（147.14±10.76）低于太冲组（156.60±8.31）和内关组（155.45±9.95），差异有统计学意义（P<0.05）。各配穴组SBP比较，太冲配内关组（194.17±8.78）、太冲配太溪组（200.22±10.52）、太冲配光明组（198.67±10.88）均低于太冲配非穴组（212.71±7.57），差异有统计学意义（P<0.05）。除模型组与非穴组外，其余各组大鼠SBP和DBP均低于治疗前，差异有统计学意义（P<0.05）。结论 针刺以太冲为主穴的不同经穴配伍对SHR血压的调节效应优于其他单穴及配穴组；针刺产生降压效应需要一定的治疗时长，针刺15天对SHR具有良好的降压效应。 |
| 英文摘要: |
| Objective To observe the effect of acupuncture on blood pressure in spontaneously hypertensive rats (SHR) by observing the effect of acupuncture on selecting taichong (LR3) as the major point plus different acupoints compatibility, and to explore the correlation between the effect of acupuncture and acupoints compatibility. Methods The 96 SHR rats were divided into model group, non-point group, Taichong (LR3) group, Neiguan (PC6) group, Taixi (KI3) group, Ligou (LR5) group, Guangming (GB37) group, Taichong (LR3) plus non-point group, Taichong (LR3) plus Neiguan (PC6) group, Taichong (LR3) plus Taixi (KI3)group, Taichong (LR3) plus Ligou (LR5) group ,Taichong (LR3) plus Guangming (GB37) group, 8 rats in each group ,a total of 12 groups. Acupuncture for 30min, 1 times a day, a total of 15 times; model group without acupuncture. Before acupuncture and at the end of fifteenth days, the systolic blood pressure (SBP), diastolic blood pressure (DBP) were measured at the end of acupuncture respectively. Results Compared with the SBP of 15 days’ acupuncture, the SBP of LR3 plus PC6 group was lower than LR3 group and PC6 group; the DBP of LR3 plus PC6 group was also lower than LR3 group and PC6 group, the difference was statistically significant (P<0.05).Compared with SBP of non-point group, the LR3 plus PC6 group, LR3 plus KI3 group and LR3 plus GB37 group was lower than LR3 plus non-point group, the difference was statistically significant (P <0.05);In addition to the model group and non-point group, the SBP and DBP of other groups was lower than that before treatment, the difference was statistically significant (P<0.05).Conclusion The effect of anti-hypertension in spontaneously hypertensive rats (SHR) on selecting Taichong (LR3) as the major point plus different acupoints compatibility is superior to other single acupoint groups; the anti-hypertension effect of acupuncture requires a certain duration of treatment, and acupuncture for 15 days has a good anti-hypertensive effect. |
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