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陈赛男,朱瑾,张琳,钱晶晶.超声引导下芯针穿刺活检在小儿腹盆腔肿瘤中诊断价值[J].浙江中西医结合杂志,2017,27(6):
超声引导下芯针穿刺活检在小儿腹盆腔肿瘤中诊断价值
Ultrasound-guided core needle biopsy in diagnosis of abdominaland pelvic neoplasm in pediatric patients
投稿时间:2016-10-25  修订日期:2017-04-11
DOI:
中文关键词:  超声  芯针穿刺活检  小儿肿瘤  腹部肿块  盆腔肿块
英文关键词:Ultrasound  Core needle biopsy  Pediatric tumor  Abdominal mass  Pelvic mass
基金项目:
作者单位E-mail
陈赛男* 杭州市儿童医院 tracyart@126.com 
朱瑾 杭州市儿童医院特检科  
张琳 浙江大学医学院附属儿童医院超声科浙江杭州  
钱晶晶 杭州市儿童医院特检科
浙江大学医学院附属儿童医院超声科浙江杭州 
 
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中文摘要:
      【】目的 探讨超声引导下芯针穿刺活检在小儿腹盆腔肿瘤中的诊断意义。方法 2013年4月-2016年4月我院收治的经临床或超声诊断出腹盆部肿块,并行超声引导下芯针穿刺活检的105例小儿患者。 结果 穿刺活检结果发现86例恶性肿瘤(其中有30例神经细胞瘤,15例肝母细胞瘤,11例肾母细胞瘤和6例原始神经外胚叶肿瘤/恶性小圆细胞瘤)和19例良性病灶(其中有10例成熟畸胎瘤,3例血管内皮细胞瘤,2例副神经节瘤和2例感染)。活检恶性肿瘤组86例患儿均经手术治疗或手术取材活检,其中有1例恶性小圆细胞瘤和2例成神经细胞瘤手术标本和穿刺活检病理诊断不一致(准确率96.5%)。穿刺活检良性肿瘤准确为100%。5例患儿穿刺活检手术后出现并发症,包括疼痛(2例),穿刺处出血(2例)和感染(1例)结论 超声引导下芯针穿刺活检是检测小儿腹盆腔肿瘤的有效、安全和微创的诊断方法。
英文摘要:
      Objective To investigate the ultrasound-guided core needle biopsy in the evaluation and diagnosis of pediatric neoplasm. Methods Data of the application of ultrasound-guided core needle biopsy in 105 pediatric patients with clinically or ultrasound-diagnosed abdominopelvic masses were reviewed. Diagnostic procedures were conducted in our institution from April 2014 to April 2016. Results The biopsies were conducted on 86 malignant lesions and 19 benign lesions. 86 malignant tumors comprised neuroblastomas (30 cases), hepatoblastomas (15 cases), nephroblastomas (11 cases), and primitive neuroectodermal tumors (6 cases). The biopsies for 1 malignant small round cells tumor and 2 neuroblastomas did not receive a pathological diagnosis. Therefore, 96.5 % of the malignant tumor patients received complete diagnosis via biopsy. 19 benign tumors comprised mature teratoma (10 cases), hemangioendothelioma (3 cases), paraganglioma (2 cases), and infection (2 cases). The diagnostic accuracy for benign neoplasm was 100 %. Five patients experienced postoperative complications, including pain (2 patients), bleeding from the biopsy site (2 patients), and wound infection (1 patient). Conclusion Ultrasound-guided core needle biopsy is an efficient, minimally invasive, accurate, and safe diagnostic method that can be applied in the management of abdominal or pelvic mass of pediatric patients.
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