| 张东伟,谢晶军.脉血康胶囊对急性脑梗死患者疗效及作用机制的研究[J].浙江中西医结合杂志,2017,27(3): |
| 脉血康胶囊对急性脑梗死患者疗效及作用机制的研究 |
| Effect and Mechanism of Maixuekang Capsule on Patients with Acute Cerebral Infarction |
| 投稿时间：2016-08-05 修订日期：2016-10-14 |
| DOI： |
| 中文关键词: 脉血康胶囊 急性脑梗死 作用机制 安全性 神经功能 |
| 英文关键词:Maixuekang Capsule Acute Cerebral Infarction Mechanism of Action |
| 基金项目:湖州市医药卫生科技计划项目一般项目 |
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| 中文摘要: |
| 目的 探讨研究脉血康胶囊对急性脑梗死患者疗效及作用机制。方法 抽取2014年6月-2015年12月我院接收的符合研究标准的74例急性脑梗死患者,随机分为观察组与对照组,各37例。对照组行降血脂、抗血小板。清除氧自由基、抗凝等常规治疗,观察组在对照组治疗基础上采用脉血康胶囊。对比两组治疗前后神经功能及生活质量评分变化情况、临床疗效、凝血功能各项指标及血液流变学各指标水平变化情况和不良反应发生情况。结果 经治疗,观察组神经功能评分(8.53±2.02)及生活质量评分(67.38±4.17)优于对照组神经功能评分(15.28±3.19)及生活质量评分(55.02±4.48),差异有统计学意义(P＜0.05)。观察组治疗总有效率为91.89%优于对照组72.97%,组间比较差异有统计学意义(P＜0.05)。经治疗,观察组各项实验指标水平优于对照组,差异有统计学意义(P＜0.05)。经治疗,观察组红细胞沉降率(15.59±4.37)及血浆粘度(2.19±0.19)水平明显优于对照组红细胞沉降率(18.64±4.77)及血浆粘度(2.34±0.17),差异有统计学意义(P＜0.05)。结论 在常规用药基础上采用脉血康胶囊治疗急性脑梗死患者疗效确切,可有效改善患者神经功能、凝血功能及血液流变学水平,提高治疗效果,且具有一定安全性。 |
| 英文摘要: |
| [Abstract] Objective To explore the curative effect and mechanism of Maixuekang Capsule for the treatment of patients with acute cerebral infarction. Methods 74 patients with acute cerebral infarction whose conditions were in line with the admission criteria of our hospital between June 2014 and December 2015 were randomly divided into an observation group and a control group, with 37 cases in each group. Conventional therapy of blood lipid reduction, anti-platelet and scavenging oxygen free radicals and anticoagulation were given to patients in the control group, whereas those in the observation group were treated by Maixuekang Capsule in additional to the treatment given to the control group. The changes of nerve function, life quality, blood coagulation indexes and hemorheology indices, adverse reactions and clinical curative effects in two groups were compared in the two groups before and after treatment. Results After treatment, the nerve function score in the observation group was (8.53±2.02) and life quality score (67.38±4.17), better than those in the control group, which were respectively (15.28±3.19) and (55.02±4.48), and the difference was statistically significant (P<0 5). The total efficiency in the observation group was 91.89%, higher than the 72.97% in control group, with significant difference between the two groups (P<0.05). After treatment, the level of each experimental index in the observation group was all better than that in the control group, and the difference was statistically significant (P<0.05). After treatment, erythrocyte sedimentation rate in the observation group (15.59.±4.37) and plasma viscosity (2.19±0.19), both significantly better than the that in the control group, which was respectively (18.64±4.77) and (2.34±0.17), where the difference was statistically significant (P<0.05). Conclusion Maixuekang Capsule combined with conventional therapy is with better curative effect in the treatment of acute cerebral infarction, which can effectively improve the neurological function, blood coagulation function, blood rheology and therapeutic effect, and is also with certain safety. |
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