| 邱慧明,熊斌.小儿消化性溃疡幽门螺杆菌感染的相关危险因素分析[J].浙江中西医结合杂志,2017,27(1): |
| 小儿消化性溃疡幽门螺杆菌感染的相关危险因素分析 |
| Risk factors of Helicobacter pylori Infection in children with peptic ulcer disease |
| 投稿时间：2016-06-16 修订日期：2016-12-01 |
| DOI： |
| 中文关键词: 小儿消化性溃疡 幽门螺杆菌 危险因素 |
| 英文关键词:children with peptic ulcer Helicobacter pylori risk factors |
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| 中文摘要: |
| 【】 目的：探讨小儿消化性溃疡幽门螺杆菌感染的相关危险因素。方法：选取2013年4月至2015年9月在我院就诊的消化性溃疡患儿148例,根据实验室检查分为HP阴性组(n=97例)和HP阳性组(n=51例),采用调查问卷的形式询问并记录患儿各项环境因素(父母文化、个人卫生、家庭经济条件、家族胃肠道病史以及既往病史等),同时检测ABO血型和Lewis血型,筛查消化性溃疡小儿HP感染的危险因素。结果：HP阳性组在年龄、性别以及母乳喂养方面与HP阴性组无统计学意义(c2=1.87,1.56,均P>0.05),在父母教育程度、个人卫生、生活地区、家庭经济状况、家族有胃肠道疾病、既往病史方面与HP阴性组有统计学差异(c2=10.65,11.49,9.66,5.76,17.89,12.51,均P>0.05)；多因素Logistic回归分析结果显示,父母文化程度、个人卫生、生活地区、家族有胃肠道疾病、既往病史、血型为O型、Lewis血型为Le(a+b+)表型均为小儿消化性溃疡幽门螺杆菌阳性的危险因素。结论：父母文化程度、小儿个人卫生、生活地区、家族有胃肠道疾病、既往病史、血型为O型、Lewis血型为Le(a+b+)表型为小儿消化性溃疡幽门螺杆菌阳性的危险因素,应加强对家长的教育和宣传,尤其是O型血和Le(a+b+)表型更应该注意。 |
| 英文摘要: |
| Objective: To evaluate the risk factors of Helicobacter pylori infection in children with peptic ulcer. Methods: From April 2013 to September 2015, 148 cases of children who were diagnosed with peptic ulcer were divided into HP-negative group (n = 97) and HP-positive group (n = 51) by examining in our hospital. Environmental factors (parents" education, hygiene, family economic conditions, family history and past medical history of gastrointestinal etc.) were investigate by questionnaire. ABO blood group and Lewis blood were detected simultaneously. Risk factors of HP infection in peptic ulcer were analyzed. Results: There was no significant difference in age, gender, and breastfeeding between HP -positive group and HP-negative group (c2=1.87,1.56, P>0.05). Parents" education level, personal hygiene, living area, family economic status, family stomach intestinal diseases, past medical history aspect statistically significant (c2=10.65,11.49,9.66,5.76,17.89,12.51, P>0.05) of HP -positive group were poorer than HP-negative group. Multivariate Logistic regression analysis showed that parents" education level, personal hygiene, life area, family gastrointestinal illness, past medical history, blood type is O, Lewis blood type Le (a + b +) phenotype in children were risk factors for Helicobacter pylori infection in peptic ulcer. Conclusion: The education level of parents, children personal hygiene, living area, family gastrointestinal illness, past medical history, blood type is O, Lewis blood type Le (a + b +) phenotype were risk factors of H. pylori infection in children with peptic ulcer factor, should strengthen children"s education and propaganda, especially type O blood and Le (a + b +) phenotype should pay more attention. |
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