| 程祖胜,夏国园,曹世林,诸绍锋,戚洪阳.松果体钙化与青少年精神分裂症的CT相关分析[J].浙江中西医结合杂志,2016,26(12): |
| 松果体钙化与青少年精神分裂症的CT相关分析 |
| Computed Tomography correlation analysis of Pineal Calcification and Adolesent Schizophrenia |
| 投稿时间：2016-06-12 修订日期：2016-10-30 |
| DOI： |
| 中文关键词: 青少年 精神分裂症 松果体 钙化 CT |
| 英文关键词:Adolescent Schizophrenia Pineal Calcification Computed tomography |
| 基金项目:绍兴文理学院医学院人才基金 |
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| 中文摘要: |
| 目的 研究松果体钙化(PC)与青少年精神分裂症(AS)的相关性。方法 回顾性分析80例经临床确诊的AS患者的脑部CT图像，观察患者的松果体有无钙化并测量其大小，并与对照组(n=60)的脑部CT 图像进行对照研究，经过统计学处理后，分析PC在患者组与对照组之间的差异及PC大小与患者年龄之间的相关性。结果 (1)PC在CT图像上表现为点状高密度影,边界清楚。(2)患者组PC45例，其中男25例,女20例，发生率为56.25%(45/80)，对照组PC17例，其中男10例,女7例，发生率28.33%（17/60）。AS患者PC发生率明显高于对照组(x2=10.83，P=0.001)。(3)AS患者组或对照组，男女性别PC发生率均无明显差异(x2=0.14，P=0.44；x2=0.29，P=0.40)。(4)AS患者PC大小随患者年龄增加而增大，呈正相关（r=0.93，P<0.001）。结论 松果体钙化在青少年精神分裂症患者中的发生率高于对照组，松果体钙化大小与患者年龄呈正相关，提示松果体钙化可能与精神分裂症的发病相关。 |
| 英文摘要: |
| Objective To investigate the correlation of pineal calcification(PC) and adolesent schizophrenia(AS).Methods Retrospective analysis the brain CT image of 80 cases who were diagnosed AS clinically,to observe whether the pineal has calcification and to measure its size.Meanwhile,compared with the healthy matched groups(n=60). After statistical treatment, Analysis of the differences between the patients group with pineal calcification and the controls and the correlation between the size of the pineal calcification and the age of the patients.Results (1)The pineal calcification presented punctuate-like high density shadow on CT?image and the boundary was clear.(2)There were 45 cases(male25, female20) with pineal calcification in the AS patients,the incidence of pineal calcifycation was 56.25%(45/80) .However, there were only17 cases (male10, female7) of pineal calcification in the control groups,the incidence was 28.33%(17/60).The incidence of pineal calcification in AS patients was significantly higher than that in control group (x2=10.83,P=0.001).(3)There was no significant difference in the incidence of pineal calcification between male and female in AS patients or control group (x2=0.14,P=0.44;x2=0.29，P=0.40).(4)The size of pineal calcification in AS patients increased with the age, and was positively correlated(r=0.92,P<0.001).
Conclusion The incidence of pineal calcification in AS patients was higher than that in the control group,the size of pineal calcification was positively correlated with the age of the patients,the pineal calcification may be be related to the pathogenesis of schizophrenia. |
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