| 楼雅芳.降气纳肾法治疗慢性阻塞性肺疾病稳定期的临床疗效观察[J].浙江中西医结合杂志,2016,26(7): |
| 降气纳肾法治疗慢性阻塞性肺疾病稳定期的临床疗效观察 |
| Clinical Observation of jiangqinashen Treatment of Chronic Obstructive Pulmonary Disease in Stable Period |
| 投稿时间：2015-11-09 修订日期：2016-04-14 |
| DOI： |
| 中文关键词: 慢性阻塞性肺疾病 稳定期 降气纳肾 噻托溴铵 临床观察 |
| 英文关键词:Chronic obstructive pulmonary disease remission jiangqinashen tiotropium clinical observation |
| 基金项目:杭州市科技发展计划 项目编号：20110833B22。 |
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| 中文摘要: |
| 摘要：目的：探讨降气纳肾法对慢性阻塞性肺疾病缓解期患者的治疗作用。方法：采用前瞻性随机对照设计，将120例慢性阻塞性肺疾病缓解期肺功能分级为Ⅱ或Ⅲ级的患者，随机分为对照组60例及治疗组60例，对照组予噻托溴铵粉吸入剂18ug吸入联合安慰剂治疗为主，治疗组则加用降气纳肾法中药，疗程为3个月。观察中医临床证候、肺功能、活动耐量及急性发作次数的变化。结果：①研究显示两组COPD患者经治疗后中医证候积分有明显改善（P<0.05），而治疗组治疗后的改善作用更为显著（P<0.05）。②经治疗后，两组的6min步行试验都得到了改善，治疗组改善程度大于对照组（P>0.05）。③经治疗后，两组之间的肺功能都得到了改善，但是治疗组和对照组之间不存在明显的差异（P>0.05）。④相比于治疗前，治疗中的两组患者急性发作次数都有下降（P<0.05），但是对照组和治疗组之间不存在明显的差异（P>0.05）。结论：降气纳肾法治疗慢性阻塞性肺疾病稳定期患者可以改善中医临床证候及活动耐量。 |
| 英文摘要: |
| Abstract: Objective: This study investigated effects of Traditional Chinese Medicine in treating COPD patients who are in remittent stage. Method: using a prospective randomized controlled design, we equally divided 120 cases of COPD patients whose lung function were classified as level Ⅱor Ⅲ into two groups: the treatment group and the control group. The treatment group were given Tiotropium 18ug qd and placebo, while the control group were treated by the herbs of Jiangqinashen. After three months treatment, we collected observations of clinical symptom, Lung function, activity tolerance, and the number of acute episodes. Results: Study showed that after treatment, both groups symptom scores had improved significantly (P<0.05), while that of the
treatment group had improved more significantly (P<0.05). As well as 6 minute walk test.However, two groups’ Lung function, FEV1%pred, showed no statistical significant differences (P>0.05). Compared to the before treatment, the acute attack times of the two groups of patients after treatment have decreased (P <0.05), but significant differences does not exist between the control group and the treatment group (P>0.05).Conclusion: treating COPD patients with Jiangqinashen Herbs improves patients clinical symptoms and activity tolerance.
Keywords: Chronic obstructive pulmonary disease; remission; jiangqinashen; tiotropium; clinical observation |
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