| 陶红,商宏恺,仝进毅.产前应用糖皮质激素对胎儿下丘脑-垂体-肾上腺（HPA）轴发育的影响[J].浙江中西医结合杂志,2016,26(5): |
| 产前应用糖皮质激素对胎儿下丘脑-垂体-肾上腺（HPA）轴发育的影响 |
| The Effect of Prenatal Glucocorticoids Treatment on the Development of the Hypothalamic-pituitary-adrenal Axis in the Fetus |
| 投稿时间：2015-10-07 修订日期：2016-01-21 |
| DOI： |
| 中文关键词: 糖皮质激素 HPA轴 远期疾病 |
| 英文关键词:Glucocorticoids HPA axis long-term disease |
| 基金项目:浙江省自然科学基金(LQ15H040002)杭州市科技发展计划项目(20140733Q06) |
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| 中文摘要: |
| 胎儿暴露于内源性或外源性糖皮质激素对胎儿的生长发育、儿童的认知能力及长远疾病有着重要影响。这些疾病风险都可能与改变了胎儿下丘脑-垂体-肾上腺（HPA）轴的生长发育相关，并且这些改变可能是永久性的。因而充分研究GCs对HPA轴的作用机制是至关重要的，这将对产前应用糖皮质激素有着重要指导意义。 |
| 英文摘要: |
| Exposure to endogenous or exogenous glucocorticoids（GCs） greatly influenced fetal growth and development, the cognitive ability and the long-term disease, possibly associated with the changes on the Hypothalamic-pituitary-adrenal (HPA) Axis, which would permanently exist. Thus, it is important to investigate the mechanism of GCs on the HPA axis, which will be of great significance to the prenatal glucocorticoid treatment. |
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