周银姬,戴蓉,徐小红.中性粒细胞与淋巴细胞比值与2型糖尿病患者颈动脉内膜增厚的相关分析[J].浙江中西医结合杂志,2016,26(1): |
中性粒细胞与淋巴细胞比值与2型糖尿病患者颈动脉内膜增厚的相关分析 |
Correlative analysis of neutrophil lymphocyte ratio with the intima-media thickening of the carotid artery of patients with type 2 diabetes mellitus |
投稿时间:2015-07-06 修订日期:2015-07-06 |
DOI: |
中文关键词: 中性粒细胞与淋巴细胞比值 2型糖尿病 颈动脉内膜增厚 危险因素 |
英文关键词:Neutrophil lymphocyte ratio Type 2 diabetes mellitus Intima-media thickening of carotid artery Risk factor |
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中文摘要: |
目的:揭示中性粒细胞与淋巴细胞比值与2型糖尿病患者颈动脉内膜增厚的关系。方法:选取166例2型糖尿病患者,采用超声检查筛查颈动脉内膜增厚,多因素分析中性粒细胞与淋巴细胞比值与2型糖尿病患者颈动脉内膜增厚的关系,ROC曲线分析中性粒细胞与淋巴细胞比值对2型糖尿病患者颈动脉内膜增厚的判断价值。结果:颈动脉内膜增厚80例(48.2%)。中性粒细胞与淋巴细胞比值是2型糖尿病颈动脉患者内膜增厚的独立危险因素(OR=9.800, 95%CI=4.415~21.756),对2型糖尿病患者颈动脉内膜增厚有显著判断价值(曲线下面积=0.802, 95%CI=0.733-0.860)。结论:中性粒细胞与淋巴细胞比值和2型糖尿病患者颈动脉内膜增厚显著相关。 |
英文摘要: |
[ive] Objective: To investigate the relationship between neutrophil lymphocyte ratio and the intima-media thickening of the carotid artery of patients with type 2 diabetes mellitus. Methods: 166 patients with type 2 diabetes mellitus were recruited. The intima-media thickening of carotid artery was screened using an ultrasonic examination. The relationship between neutrophil lymphocyte ratio and the intima-media thickening of the carotid artery of patient with type 2 diabetes mellitus was evaluated using a multivariate analysis. The identifiable value of neutrophil lymphocyte ratio for the intima-media thickening of the carotid artery of patient with type 2 diabetes mellitus was assessed using a ROC analysis. Results: 80 patients (48.2%) had the intima-media thickening of the carotid artery. Neutrophil lymphocyte ratio emerged as an independent risk factor for the intima-media thickening of the carotid artery of patient with type 2 diabetes mellitus (OR=9.800, 95%CI=4.415~21.756) and possessed the obvious identifiable value for the intima-media thickening of the carotid artery of patient with type 2 diabetes mellitus (area under curve=0.802, 95%CI=0.733-0.860). Conclusion: Neutrophil lymphocyte ratio is related closely to the intima-media thickening of the carotid artery of patients with type 2 diabetes mellitus. |
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