| 林少华,章浙忠,骆丰,陈燕.慢性鼻炎-鼻窦炎菌群分布及耐药性观察[J].浙江中西医结合杂志,2015,25(10): |
| 慢性鼻炎-鼻窦炎菌群分布及耐药性观察 |
| Chronic rhinosinusitis flora distribution and drug resistance observation |
| 投稿时间：2015-03-24 修订日期：2015-06-05 |
| DOI： |
| 中文关键词: 慢性鼻-鼻窦炎 细菌培养 药敏试验 |
| 英文关键词:chronic rhinosinusitis bacterial culture drug sensitivity test |
| 基金项目:浙江省中医药科技计划项目2013ZB059 |
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| 中文摘要: |
| 目的 了解慢性鼻-鼻窦炎(CRS)患者窦腔的菌群分布及药敏情况。方法 收集76例CRS 患者窦腔脓液和病变黏膜行细菌培养和药敏试验, 分析监测结果。结果 76例送检标本, 阳性62例, 阳性率为81.58%, 其中金黄色葡萄球菌29株,表皮葡萄球菌10 株, 肺炎克雷伯菌5 株,铜绿假单胞菌和化脓性链球菌各3株,臭鼻克雷伯菌、大肠埃希菌及溶血葡萄球菌各2株,异型枸橼酸杆菌等6个菌种各1株。分离菌株对常用抗生素敏感度: 替加环素100%、莫西沙星91.30%、力奈唑烷100%、红霉素90.70,利福平100%,万古霉素100%, 庆大霉素92.22%, 复方新诺明71.19%, 亚胺培南100%, 丁胺卡那100%, 氨苄西林/ 舒巴坦86.67%, 头孢曲松66.67%,哌拉西林/他唑巴坦100%, 青霉素13.04% 。结论 CRS多伴有细菌感染,大环内酯类可作为本地区慢性鼻-鼻窦炎的首选抗生素 |
| 英文摘要: |
| OBJECTIVE To investigate distribution and drug-susceptibility of bacteria in patients with chronic rhinosinusitis. METHODS The purulent discharges or mucous membrane lesions were collected from the sinus of 76 patients with chronic rhinosinusitis .The clinical specimens were incubated and the drug susceptibility was analyzed. RESULTS Of 76 specimens,62( 81.58%) showed positive results in bacteria culture. Which S.aureus 29, S.epidermidis 10, K.pneumoniae 5, P.aeruginosa and S.pyogenes all three, K.ozaenae, E. coli and S.hemolyticus each two, C.diversus and other six species each one .The antibiotic susceptibility was as follows: Tigecycline-100%,moxifloxacin-91.30%,Linezolid-100%,Erythromycin-90.70%,rifampin-100%,vancomycin-100%,Gentamicin-92.22%,SMZ-TMP-71.19%,Imipenem-100%, Amikacin-100%, Ampicillin-Sulbactam-86.67%, cefatriaxo-66.67%, Piperacillin and tazobactam-100 %, penicillin-13.04%.CONCLUSIONS There are bacteria infections in most of chronic rhinosinusitis. Macrolide antibiotics can be used as the preferred local chronic rhinosinusitis. |
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