| 蔡皎皓,沈淑荣.六神丸联合盐酸羟考酮缓释片治中重度癌痛疗效观察[J].浙江中西医结合杂志,2015,25(8): |
| 六神丸联合盐酸羟考酮缓释片治中重度癌痛疗效观察 |
| Treatment Observation on Six spritits pills Combinedwith Oxycodone for Moderate or Severe Cancer Pain |
| 投稿时间：2014-12-01 修订日期：2015-05-25 |
| DOI： |
| 中文关键词: 癌痛 六神丸 盐酸羟考酮缓释片 |
| 英文关键词:severe cancer pain Six spritits pills Oxycodone hydrochloride |
| 基金项目: |
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| 中文摘要: |
| 【】 目的评价六神丸联合盐酸羟考酮缓释片治中重度癌痛的有效性。方法 观察六神丸联合盐酸羟考酮控释片(奥施康定)治疗肿瘤中重度疼痛的临床疗效。通过对有中、重度疼痛的65名肿瘤骨转移患者随机分组,连续观察2周期(28d), 采用χ2检验, 对两组疼痛缓解情况、 盐酸羟考酮控释片(奥施康定)用药剂量、 生活质量评分情况进行观察和分析。结果 治疗后治疗组疼痛缓解情况明显优于对照组(P<0.05)；治疗组盐酸羟考酮控释片使用量增加率低于对照组(P<0.05)；两组生活质量评分提高率比较,治疗组高于对照组(P<0.05)。结论 六神丸对治疗中重度肿癌痛有明显提高止痛作用的效果,可减少强阿片类药物羟考酮的使用剂量, 对提高患者生存质量有重要意义。 |
| 英文摘要: |
| 【】Objective:To observe the short- term efficacy,adverse reaction of Six spritits pills combined with Oxyc-odone for moderate to severe cancer pain．Methods:65patients with cancer pain were randomly assigned to Six spritits pills combined with Oxycodone(trial group)group or oxycodone alone(control group)group． Two groups were observed continuously for 2 cycle(14 days),χ2test was adopted to observe and analyze pain relieving situation,dose of oxycodone hydrochloride(oxycontin)and physical state score, and the quality of life scores. |
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