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纪文健,俞文华.小剂量甘露醇联合搜风顺气汤对高血压脑出血术后脑水肿的改善[J].浙江中西医结合杂志,2016,26(5):
小剂量甘露醇联合搜风顺气汤对高血压脑出血术后脑水肿的改善
投稿时间:2014-11-19  修订日期:2015-09-22
DOI:
中文关键词:  高血压脑出血  搜风顺气汤 脑部微循环
英文关键词:
基金项目:
作者单位E-mail
纪文健* 浙江省桐庐县桐庐中医院 hztljwj@163.com 
俞文华   
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中文摘要:
      目的通过研究小剂量甘露醇联合搜风顺气汤对高血压脑出血术后脑部微循环的影响,揭示此方法治疗高血压脑出血术后脑水肿的可行性及其相关机制 方法本研究按照随机分配的原则,将60例高血压脑出血患者随机分为2组,治疗组30例辨证使搜风顺气汤,适量减轻甘露醇的用量及缩短用时,配合西医常规治疗; 对照组30例采用西医常规疗法治疗。比较2组血液流变学参数,采用经颅多普勒(TCD)检测仪对患者治疗前后患侧大脑中动脉(MCA) 的血液动力学参数变化。结果2组在血液流变学参数,血液动力学参数变化的差异上有统计学意义(p小于或等于0.01)结论 通过减少甘露醇的用量及使用时间,配合中药治疗来改善高血压脑出血术后脑部微循环障碍,从而改善高血压脑出血术后脑水肿。
英文摘要:
      【】Objective To study the small dose of mannitol combined SouFeng ShunQI Decoction on the influence of cerebral microcirculation after operation of hypertensive cerebral hemorrhage, the feasibility of this method is to reveal brain edema after the operation in treatment of hypertensive cerebral hemorrhage and its mechanism methods this study according to the randomized allocation principle, 60 cases of patients with hypertensive cerebral hemorrhage were randomly divided into 2 groups, the treatment group of 30 cases dialectical make SouFeng ShunQi decoction, reduce the amount of mannitol dosage and reduce the use of time, combined with conventional western medicine treatment; 30 cases in control group were treated with routine therapy. Parameters were compared between the 2 groups of blood rheology, transcranial Doppler (TCD) detection instrument before and after treatment in patients with bleeding side of middle cerebral artry(MCA)changes in hemodynamic parameters. Results the 2 groups in blood rheology parameter, the difference was statistically significant on the change of hemodynamic parameters (p less than or equal to 0.01) conclusions of this study are explored to reduce the dosage of mannitol and the time of use, with Chinese medicine treatment to improve after operation of hypertensive cerebral hemorrhage cerebral microcirculation obstacle, thereby improving the hypertensive cerebral hemorrhage cerebral edema.
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