| 郭俊华,黄挺,张志娣,李勇,黄伶,杨雪飞,张建刚,张晓丽.益气通络中药浸泡疗法缓解化疗患者手足综合症的临床随机对照研究[J].浙江中西医结合杂志,2015,25(6): |
| 益气通络中药浸泡疗法缓解化疗患者手足综合症的临床随机对照研究 |
| The immersion therapy of Chinese drug in the treatment of hand-foot syndrome induced by Capecitabine :A randomised controlled trial |
| 投稿时间：2014-11-15 修订日期：2015-02-03 |
| DOI： |
| 中文关键词: 中药浸泡 化疗 手足综合症 |
| 英文关键词:immersion therapy of Chinese drug Chemotherapy hand-foot syndrome |
| 基金项目:浙江省中医药科技计划项目（编号：2012ZA095） |
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| 中文摘要: |
| 目的：观察益气通络中药浸泡疗法在缓解卡培他滨所致手足综合症方面的临床疗效；方法：46例接受卡培他滨化疗的肿瘤患者,随机分为中药浸泡组及对照组各23例。对两组患者手足综合症及相关不良事件发生率进行统计学分析,评价益气通络中药浸泡疗法在改善化疗手足综合症及相关不良事件方面的效果；结果：益气通络中药浸泡疗法可明显降低手足综合症的发生率,其效果随化疗疗程的增加而逐步明显(P<0.05)；益气通络中药浸泡疗法可减少化疗延期、减量或终止的病例数(P<0.05)；结论：益气通络中药浸泡疗法可降低化疗期间手足综合症的发生率,及因此导致的化疗药物减量、疗程延期或终止等不良事件的发生率。 |
| 英文摘要: |
| Objective: To observe the curative effect of the immersion therapy of Chinese drug in the treatment of hand-foot syndrome induced by Capecitabine. Methods: 46 cancer patients who received the chemotherapy of capecitabine were divided into the immersion group and the controlled group. To compare the differences in the incidence rates of the HFS and its related adverse between this two groups systematically. Result: The immersion therapy of Chinese drug could reduce the incidence of HFS, especially during the later cycles of the chemo, which shows a significant difference contrast with the controlled group (P<0.05). In the immersion group, chemotherapy circle was rarely delayed, diminished or canceled, the difference between these two groups was also obviously (P<0.05). Conclusion: By applying the immersion therapy of Chinese drug to the chemotherapy, the incidence of HFS and its related adverse events can be diminished remarkably than single chemotherapy. |
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