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陆峰,马震,唐坚强.十二指肠神经内分泌肿瘤CT影像学特点[J].浙江中西医结合杂志,2015,25(6):
十二指肠神经内分泌肿瘤CT影像学特点
CT performances of neuroendocrine neoplasm of the duodenumLu Feng1, Ma Zhen1, Tang Jian-qiang2
投稿时间:2014-10-08  修订日期:2014-12-15
DOI:
中文关键词:  神经内分泌肿瘤 十二指肠 体层摄影术 X线计算机
英文关键词:Neuroendocrine neoplasm  Duodenum  Tomography, X-ray Computed
基金项目:
作者单位E-mail
陆峰* 平湖市第一人民医院 71054514@qq.com 
马震   
唐坚强   
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中文摘要:
      【】 目的 分析十二指肠神经内分泌肿瘤的CT影像学特点,旨在提高对该病的认识。 方法 回顾性分析经手术或穿刺活检病理证实的12例十二指肠原发性神经内分泌肿瘤的多层螺旋CT表现。 结果 肿瘤好发于十二指肠降段(球部2例,降段9例,水平段1例);肿瘤最大直径1.2~5.8cm,平均2.1±0.3cm;8例表现为腔内息肉样肿块或乳头状结节,3例表现为壁内肿块或肠壁局限性增厚、隆起,1例表现为位于腔内外的肿块;病灶大多边缘光整,部分壁内病灶仅表现为粘膜局部隆起。肿瘤多呈等密度且密度均匀(9例),平均CT值37HU,2例伴有低密度坏死区,1例病灶内见钙化;三期增强扫描早期病灶显著强化,后期强化程度逐期降低,但仍有较明显强化,平均CT值分别为107HU、84HU、67HU。引起胆道扩张6例,其中2例并有主胰管扩张;CT扫描发现肝转移1例,病理证实淋巴结转移3例,胰腺及周围系膜、血管累犯4例。 结论 十二指肠神经内分泌肿瘤的CT表现有一定的特征性,对本病有较高的诊断价值,多层螺旋CT扫描已成为首要的影像学检查方法。
英文摘要:
      【】 Objective: To analysis the CT performances of neuroendocrine neoplasm of the duodenum, and improve the understanding of the disease. Methods: In 12 patients with duodenal neuroedocrine neoplasm confirmed by operation or biopsy pathology, the features on MSCT were retrospectively analyzed. Results: Most duodenal neuroendocrine neoplasm located in the proximal duodenum (2 in the bulb, 9 in the second portion and 1 in the third portion). The neoplasm diameter ranged from 1.2-5.8cm with mean value of 2.1±0.3cm, 8 patients had focal intraluminal polypoid or papillary masses and 3 had mural masses or intestinal wall limitations uplift, and 1 case showed lesions to lumen inside and outside to grow. Most lesions showed edge finishing and some of intramural masses only showed mucosal uplift. Homogenous in 9 patients, mean CT values 37HU, heterogenous in 2 patients, with central necrosis, and calcification was found in one patient. During three-phase of intravenous contrast enhanced CT, the lesions showed obvious enhancement at arterial phase and loss of enhancement at portal venous and delayed imaging, the average CT values of three-phase was 107HU, 84HU and 67HU. Other findings included bile duct dilatation in 6 patients, and 2 of 6 patients with main pancreatic duct dilatation. CT imaging revealed liver metastasis in one patient, and pathology revealed lymphatic metastasis in 3 patients. Pancreatic gland, mesentery and vessel encroachment in 4 patients. Conclusion: CT features of neuroendocrine neoplasm of duodenum are relatively specific, MSCT scanning shows high value for the diagnosis in this disease and has become the first imaging examination.
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