| 朱仁洋,孙新芳,吴国水,肖桂荣,王黎萍,吴承龙.补阳还五汤加减联合天智颗粒治疗血管性认知障碍的临床研究[J].浙江中西医结合杂志,2015,25(2): |
| 补阳还五汤加减联合天智颗粒治疗血管性认知障碍的临床研究 |
| Study on Buyang-Huanwu decoction combined with Tianzhi granule in treating vascular cognitive impairment |
| 投稿时间：2014-07-07 修订日期：2014-08-29 |
| DOI： |
| 中文关键词: 补阳还五汤 天智颗粒 血管性认知障碍 蒙特利尔认知评估 简易智能精神量表 疗效 |
| 英文关键词:Buyang-Huanwu decoction Tianzhi granule Vascular cognitive impairment(VCI) The Montreal Cognitive Assessment(MoCA) MiNi-MentalState Examination(MMSE) Curative effect |
| 基金项目:浙江省中医药科学研究基金计划，基金号：2012ZA122 |
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| 中文摘要: |
| 目的 观察补阳还五汤加减联合天智颗粒治疗血管性认知障碍的临床疗效。方法 选择在本院住院或门诊的血管性认知障碍患者100例，随机分为观察组和对照组，每组各50例。观察组给予补阳还五汤加减并联合天智颗粒治疗，对照组予以盐酸多奈哌齐治疗。在治疗前及治疗后8周分别对观察组和对照组进行MoCA、MMSE评定进行疗效比较。结果 两组治疗后MoCA、MMSE评分均较治疗前显著改善（P<0.01），组间评分无统计学差异。结论 补阳还五汤加减联合天智颗粒对血管性认知障碍有明显改善作用。 |
| 英文摘要: |
| Objective To observe the curative effect of Buyang-Huanwu decoction combined with Tianzhi granule on vascular cognitive impairment(VCI). Methods Totally 100 patients diagnosed as having VCI were randomly divided into two groups: compound group(n=50), treated with Buyang-Huanwu decoction and Tianzhi granule; control group(n=50), treated with donepezil. All patients were assessed with The Montreal Cognitive Assessment(MoCA) and MiNi-MentalState Examination(MMSE) before treatment and after 8 weeks to evaluate efficacy. Results The MoCA and MMSE had been significantly improved together in two groups after 8 weeks of treatment(p<0.01), and there were no significant differences between two groups. Conclusions Buyang-Huanwu decoction combined with Tianzhi granule can be effective on patients with VCI. |
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