杨絮,应茵,李功华,王晖,孙云峰.抗精神病药物联用致恶性综合征1例[J].浙江中西医结合杂志,2015,25(3): |
抗精神病药物联用致恶性综合征1例 |
NMS due to combination therapy with antipsychotic drugs |
投稿时间:2014-05-28 修订日期:2014-07-30 |
DOI: |
中文关键词: 抗精神病药物,恶性综合征,联用 |
英文关键词:antipsychotic drugs,neurolepic malignant syndrome,combination |
基金项目: |
|
摘要点击次数: 1095 |
全文下载次数: 0 |
中文摘要: |
1例50岁女性患者,既往有28年精神分裂症史,因发热、昏迷、痰多、
呼吸费力,转入我院ICU。T 38.7℃,BP 144/ 97 mmHg。急诊实验室检查:PCT
<0.05 ng/ml, CK 1568U/L,CK-MB 46U/L。回顾患者入院前用药史:先后联用氯氮
平、齐拉西酮、坦度螺酮、劳拉西泮和舒必利等多种抗精神病药物,提出抗精神病
药物多药联用所致药物不良反应的可能。停用所有抗精神病药物,对症支持治疗,
并给予溴隐亭,治疗一周后患者症状明显改善。 |
英文摘要: |
A 50 years old woman with a history of 28 years of schizophrenia.transferred to our hospital because of fever、coma、phlegm、respiratory effort.Her temperature was 38.7℃ and blood pressure was 144/97 mmHg.Laboratory tests revealed the following values:PCT<0.05ng/ml,CK 1568U/L,CK-MB 46U/L。Recall medication history:has combined with clozaphine,ziprasidone,tandospirone,lorazepam and sulpiride other antipsychotics, proposed NMS case due to combination therapy with antipsychotic drugs.antipsychptic drugs were discontinued,symptomatic and supportive treatment,taking bromocriptine.After a week of treatment,the symptoms relieved obviously. |
查看全文 查看/发表评论 下载PDF阅读器 |
关闭 |
|
|
|