| 夏晓峰,董小牛,何庄建.甲状腺微小乳头状癌中央区淋巴结转移相关因素分析[J].浙江中西医结合杂志,2014,24(12): |
| 甲状腺微小乳头状癌中央区淋巴结转移相关因素分析 |
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| 投稿时间：2014-03-25 修订日期：2014-10-14 |
| DOI： |
| 中文关键词: 甲状腺微小乳头状癌 颈淋巴结清扫 中央区 |
| 英文关键词:Papillary thyroid microcarcinoma neck dissection Central area |
| 基金项目: |
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| 中文摘要: |
| 目的 分析甲状腺微小乳头状癌(PTMC)中央区淋巴结转移情况及其风险因素,为其合理治疗提供依据。方法 回顾性分析我院手术治疗的83例PTMC的临床病理资料。所有患者均行中央区淋巴结清扫。单因素分析采用χ2检验或精确概率法,多因素分析采用Logistic 回归分析。结果 术后病理显示中央区淋巴结转移率39.8%(33/83)。单因素分析结果显示病灶>5mm、腺外侵犯、多病灶以及腺内播散是PTMC中央区淋巴结转移的影响因素(P<0.05)。Logistic多因素分析显示： 肿瘤最大径>5 mm和腺内播散是PTMC中央区淋巴结转移的高危因素。结论 PTMC中央区淋巴结转移率高。病灶>5mm、腺外侵犯、多病灶和腺内播散是PTMC中央区淋巴结转移的风险因素。 对这部分PTMC,应积极行中央区淋巴结清扫。 |
| 英文摘要: |
| Objective To investigate the metastatic rate of lymph node in neck central area of papillary thyroid microcarcinoma (PTMC) and its risk factors. Methods Clinicopathologic data of 83 patients with PTMC were reviewed. All patients received central compartment neck dissection. Univariate analysis used by χ2 test or Fisher"s exact. Multivariate analysis was performed by Logistic regression model. Results Postoperative pathology showed that the the metastatic rate of lymph node in neck central area was 39.8%(33/83). Univariate analysis showed that tumor larger than 5mm, extraglandular invasion, multifocal disease and intraglandular dissemination were the influence factors of central neck metastasis of PTMC (p<0.05). Logistic analysis showed that tumor larger than 5mm and intraglandular dissemination were the risk fators of central neck metastasis of PTMC. Conclusions The metastatic rate of lymph node in neck central area was high. Tumor larger than 5mm, extraglandular invasion, multifocal disease and intraglandular dissemination were the risk fators of central neck metastasis of PTMC and central compartment neck dissection should be more positive for these patients. |
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