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王京霞,蒋剑平,陈琳,许家鸾.小儿清热栓对家兔退热作用的影响[J].浙江中西医结合杂志,2014,24(8):
小儿清热栓对家兔退热作用的影响
Effects of Xiaoer Qingre suppository antipyretic action on rabbits
投稿时间:2014-03-10  修订日期:2014-04-29
DOI:
中文关键词:  小儿清热栓  家兔  退热作用  对乙酰氨基酚栓。
英文关键词:Xiaoer Qingre suppository  rabbit  antipyretic effect  Paracetamol suppository
基金项目:小儿清热栓剂的研究与开发
作者单位E-mail
王京霞* 浙江省中医院(浙江中医药大学附属第一医院) 962039277@qq.com 
蒋剑平   
陈琳   
许家鸾   
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中文摘要:
      目的:对小儿清热栓的退热作用进行实验研究。方法:采用内毒素致家兔发热法观察其对正常家兔及发热家兔的退热作用。结果:从家兔退热实验可知:小儿清热栓对正常家兔体温其DT和TRI6与NS组相比无明显差异;ET组在注射ET后体温明显升高,而小儿清热栓 ET组平均体温变化明显低于ET组,且DT和TRI6与ET组相比差异非常显著。结论:小儿清热栓对正常家兔的体温无退热作用,对发热家兔具有一定的退热作用,其作用与阳性药物对乙酰氨基酚栓相当。
英文摘要:
      Objective:Experimental study on the antipyretic effect in Xiaoer Qingre suppository.Method: The observation of the antipyretic effect of endotoxin in normal rabbits and rabbits with fever.Results: The rabbit fever experiment shows: Xiaoer Qingre suppository on normal rabbit body temperatureDTand TRI6 compared with group NS had no significant difference;In ET group elevated body temperature after injection; Xiaoer Qingre suppository ET group average temperature was lower than ET group, There are significant differences compared with ET group. Conclusion: Xiaoer Qingre suppository in normal rabbits without antipyretic effect, has antipyretic effect on fever in rabbits. Its effect was similar to positive drug Paracetamol suppository.
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