| 沈博,周玮.多发原发性中枢神经系统淋巴瘤的MRI特征[J].浙江中西医结合杂志,2014,24(11): |
| 多发原发性中枢神经系统淋巴瘤的MRI特征 |
| MRI Features of Multiple Primary Central Nervous System Lymphomas |
| 投稿时间：2014-02-19 修订日期：2014-06-08 |
| DOI： |
| 中文关键词: 脑肿瘤 淋巴瘤 磁共振成像 |
| 英文关键词:Brain tumors lymphoma magnetic resonance imaging |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨多发原发性中枢神经系统淋巴瘤( MPCNSLs) 的MRI特点。方法 回顾性分析11例经病理证实的MPCNSLs的MRI资料。所有病例为免疫力正常患者，检查均行MR平扫及增强扫描。结果 11例MPCNSLs 2个病灶7例，3个病灶病例3例，4个病灶1例，共27个病灶；类圆形12个，不规则形15个；病灶周围轻度水肿13个，中度水肿9个，重度水肿5个。MR平扫T1WI呈稍低或低信号15个，等信号12个病灶；T2WI呈高信号10个，混杂等高信号17个；DWI呈高信号20个，呈低信号7个；增强扫描病灶呈团块样或握拳样强化21个，片状及结节状强化6个；轻度强化1个，中度强化2个，明显强化24个；均匀强化21个，不均匀强化6个，肿瘤对放化疗敏感，形态、大小变化明显。结论 MPCNSLs 常规MRI表现具有一定特征，为临床诊断、制定治疗方案和预后评估提供重要参考。 |
| 英文摘要: |
| Objective To investigate MRI features of multiple primary central nervous system Lymphomas . aterials and Methods MR imagings of 11 patients with MPCNSLs confirmed by pathology were analyzed retrospectively．In above mentioned cases，immunocompetent patients were executed MR routine and enhanced scan. Results In 11 cases of multiple primary central nervous system Lymphomas, each of 7 cases have 2 lesions; each of 3 cases have 3 lesions; each of 1 cases have 4 lesions. Totally, 27 lesions were finded. In which, 12 lesions were nearly circular; 15 lesions were irregular shape; 13 lesions were slight peripheral edema; 9 lesions were medium peripheral edema; 5 lesions were serious peripheral edema. In MR routine scan, T1WI of 15 lesions showed a slightly lower or low signal; T1WI of 12 lesions showed equisignal; T2WI of 10 lesions showed highsignal; T2WI of 17 lesions showed mixed high signal; DWI of 20 lesions showed high signal; DWI of 7 lesions showed low signal. In MR enhanced scan, 21 lesions showed lump or fisted enhancement; 6 lesions showed sheet or nodular enhancement; A lesion showedslight enhancement; 2 lesions showed medium enhancement; 24 lesions showed obvious enhancement; 21 lesions showed even enhancement; 6 lesions showed uneven enhancement. Tumor was sensitive to radiotherapy and chemotherapy. Its shape and size changedsignificantly after radiotherapy and chemotherapy. Conclusion MRI findings of multiple primary brain lymphoma has a certain characteristic, can provide important references for clinicaldiagnosis, treatment plan and prognosis evaluation. |
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