| 呙登俊,王浩,陈紫君,江霞,胡智伟.人参归脾汤对气血亏虚型老年颤证患者睡眠障碍的影响[J].浙江中西医结合杂志,2012,22(2):92-131 |
| 人参归脾汤对气血亏虚型老年颤证患者睡眠障碍的影响 |
| Effect of Renshenguipi Decoction on Sleep Disorder Caused by Parkinson Disease in the Aged with Syndrome of Qi and Blood Deficiency |
| 投稿时间：2011-11-10 |
| DOI： |
| 中文关键词: 老年颤证 气血亏虚型 睡眠障碍 人参归脾汤 |
| 英文关键词:Parkinson disease syndrome of qi and blood deficiency sleep disorder Renshenguipi decoction |
| 基金项目:浙江省中医药优秀青年人才项目（No.2011ZQ002） |
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| 中文摘要: |
| 目的： 研究人参归脾汤治疗气血亏虚型老年颤证睡眠障碍的临床疗效。方法： 选择气血
亏虚型老年颤证患者98 例，随机分为治疗组和对照组，对照组给予美多巴片治疗，治疗组在对照
组基础上予以人参归脾汤治疗，连用1 个月。治疗前、治疗后分别对患者进行帕金森病生活质量39
项问卷（PDQ39）、爱泼沃斯嗜睡量表（ESS）和帕金森病睡眠量表（PDSS）调查，并参照《中医老年颤
证诊断和疗效评定标准》进行疗效评定。结果：治疗1 个月后，治疗组中医疗效评定总有效率60%，
高于对照组的33.3%（P<0.01）；治疗组患者PDQ39、ESS 和PDSS 评分均低于治疗前及对照组（P<
0.01）。结论：人参归脾汤能改善气血亏虚型老年颤证患者睡眠障碍，提高患者生活质量。 |
| 英文摘要: |
| Objective: To evaluate the effect of Renshenguipi decoction on sleep disorder caused by Parkinson disease in
patients with syndrome of qi and blood deficiency in TCM. Methods: A total of 98 Parkinson patients with syndrome of qi
and blood were randomized into the treatment group (n=50) and the control group(n=48). The control group was treated
with medopa tablets. The treatment group received Renshenguipi decoction in addition to medopa. The therapy course was
one month. PDQ39 sheet, ESS sheet, and PDSS were used to evaluate the status of the patients before and after treatment,
as well as referring to "Standards of Diagnosis and Evaluation of the Elderly's Tremor Symptoms of TCM". Results: After
1-month treatment, the total response rate was 60% in the treatment group, significantly higher than that of the control
group(33.3%, P<0.01). The treatment group had lower PDQ39, ESS, and PDSS scores as compared to those before the
treatment and those in the control group(P <0.01). Conclusion: Renshenguipi decoction may attenuate sleep disorders
caused by tremors in the elderly with syndrome of qi and blood deficiency, resulting in improving their quality of life. |
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